Results 51 to 60 of about 235,905 (295)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Variation in early life maternal care predicts later long range frontal cortex synapse development in mice. [PDF]

open access: yes, 2020
Empirical and theoretical work suggests that early postnatal experience may inform later developing synaptic connectivity to adapt the brain to its environment.
Chang, Irene   +3 more
core  

Insecure attachment during infancy predicts greater amygdala volumes in early adulthood [PDF]

open access: yes, 2014
Background The quality of the early environment is hypothesized to be an influence on morphological development in key neural areas related to affective responding, but direct evidence to support this possibility is limited.
Ahnert   +62 more
core   +2 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

Genetic Regulation of Maternal Oxytocin Response and Its Influences on Maternal Behavior

open access: yesNeural Plasticity, 2016
We interrogated the genetic modulation of maternal oxytocin response and its association with maternal behavior using genetic risk scores within the oxytocin receptor (OXTR) gene.
Divya Mehta   +6 more
doaj   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund   +3 more
wiley   +1 more source

Ablating adult neurogenesis in the rat has no effect on spatial processing: evidence from a novel pharmacogenetic model.

open access: yesPLoS Genetics, 2013
The function of adult neurogenesis in the rodent brain remains unclear. Ablation of adult born neurons has yielded conflicting results about emotional and cognitive impairments. One hypothesis is that adult neurogenesis in the hippocampus enables spatial
James O Groves   +8 more
doaj   +1 more source

Female rats are resilient to the behavioral effects of maternal separation stress and exhibit stress-induced neurogenesis

open access: yesHeliyon, 2020
Early-life stress causes anxiogenesis and sensitivity of stress endocrine axis, facilitated by changes in the basolateral amygdala and hippocampal neurogenesis.
Yan Jun Lee   +3 more
doaj   +1 more source

The impact of environmental factors during maternal separation on the behaviors of adolescent C57BL/6 mice

open access: yesFrontiers in Molecular Neuroscience, 2023
Neonatal maternal separation is a widely used method to construct an early-life stress model in rodents. In this method, pups are separated from their mothers for several hours every day during the first 2 weeks of life, which results in adverse early ...
Sangyep Shin, Sukwon Lee
doaj   +1 more source

The Validity and Reability of Turkish Version of Separation Anxiety Symptoms Inventory and Adult Separation Anxiety Questionnaire

open access: yesTurkish Journal of Psychiatry, 2012
The aim of this study is to evaluate the validity and reliability of Separation Anxiety Symptoms Inventory (SASI) that assess childhood separation anxiety retrospectively and Adult Separation Anxiety Questionnaire (ASA).The study sample included a group of 410 participants comprised of 282 adult psychiatric outpatients with anxiety and/or major ...
Onur, Elif   +4 more
openaire   +3 more sources

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