Results 61 to 70 of about 3,058,602 (268)

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

The characteristics of the comorbidity between social anxiety and separation anxiety disorders in adult patients

Nordic Journal of Psychiatry, 2019
Objective: In the present study, we compared social anxiety disorder (SAD) patients with (n = 31) and without childhood and adulthood separation anxiety disorder (SeAD) (n = 50) with respect to suicidal behavior, avoidant personality disorder (AvPD), other anxiety disorders (ADs), and major depression as well as some sociodemographic variables. Methods:
Bilge Dogan, Caner Yoldas, Oktay Kocabas, Cagdas Oyku Memis, Doga Sevincok, Levent Sevincok   +5 more
openaire   +2 more sources

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Local and regional heterogeneity underlying hippocampal modulation of cognition and mood

Frontiers in Behavioral Neuroscience, 2014
While the hippocampus (HPC) has been classically studied for its role in learning and memory, there is significant support for a role of the HPC in regulating emotional behavior.
Lindsay eTannenholz, Jessica C Jimenez, Mazen A Kheirbek   +2 more
doaj   +1 more source

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

Examination of the relationship between attachment styles, separation anxiety and rejection sensitivity in social anxiety disorder

Medicine Science
Social anxiety disorder is a significant mental health illness that causes marked functional impairment. This study hypothesizes that rejection sensitivity, insecure attachment, and separation anxiety will be higher in people with social anxiety disorder
Fatma Gul Helvaci Celik, Meltem Pusuroglu, Mehmet Baltacioglu, Cicek Hocaoglu, Bulent Bahceci   +4 more
doaj   +1 more source

Effects of Early-Life Stress on Social and Anxiety-Like Behaviors in Adult Mice: Sex-Specific Effects

Behavioural Neurology, 2018
Stressful events in an early postnatal period have critical implications for the individual’s life and can increase later risk for psychiatric disorders.
Natalya P. Bondar, Arina A. Lepeshko, Vasiliy V. Reshetnikov   +2 more
doaj   +1 more source

Ablating adult neurogenesis in the rat has no effect on spatial processing: evidence from a novel pharmacogenetic model.

PLoS Genetics, 2013
The function of adult neurogenesis in the rodent brain remains unclear. Ablation of adult born neurons has yielded conflicting results about emotional and cognitive impairments. One hypothesis is that adult neurogenesis in the hippocampus enables spatial
James O Groves, Isla Leslie, Guo-Jen Huang, Stephen B McHugh, Amy Taylor, Richard Mott, Marcus Munafò, David M Bannerman, Jonathan Flint   +8 more
doaj   +1 more source

Female rats are resilient to the behavioral effects of maternal separation stress and exhibit stress-induced neurogenesis

Heliyon, 2020
Early-life stress causes anxiogenesis and sensitivity of stress endocrine axis, facilitated by changes in the basolateral amygdala and hippocampal neurogenesis.
Yan Jun Lee, Amelia S. Koe, Archana Ashokan, Rupshi Mitra   +3 more
doaj   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source