Developmental Cognitive Neuroscience, 2022 Adverse early life experiences, such as maternal separation, are associated with an increased risk for several mental health problems. Symptoms induced by maternal separation that mirror clinically relevant aspects of mental problems, such as cognitive ...
Bo Ou-Yang +6 more
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Maternal separation during breastfeeding as a risk factor for developing giardiasis: evaluation in a rodent model [PDF]
Gut PathogensBackground Giardia lamblia is a globally prevalent gastrointestinal parasite. Breastfeeding provides protective effects against infections, but the impact of early life stress, such as maternal separation, on G. lamblia infection remains unclear.
M. F. Gerena-Cruz +4 more
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Dissociative symptoms in school-aged adopted children who experienced maternal separation and disruptive caregiving in infancy [PDF]
Frontiers in PsychiatryAmounting findings on maternal separation and early disturbed caregiving suggest that this type of early experience negatively influences socioemotional development and may be associated with behavioral and mental health problems in later life ...
Petra Winnette +3 more
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One-Week Maternal Separation Caused Sex-Specific Changes in Behavior and Hippocampal Metabolomics of Offspring Rats [PDF]
Brain SciencesTo investigate the effects of one-week maternal separation (MS) on anxiety- and depression-like behaviors in adolescent and adulthood as well as adult hippocampal metabolomics simultaneously in offspring female and male rats.
Meng-Chen Dong +6 more
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Combined Effect of Maternal Separation and Early-Life Immune Activation on Brain and Behaviour of Rat Offspring [PDF]
BiomoleculesAdversity during early life, a critical period for brain development, increases vulnerability and can have a lasting impact on the brain and behaviour of a child.
Bharti Biswas +3 more
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Activation of EphrinB2/EphB2 signaling in the spine cord alters glia-neuron interactions in mice with visceral hyperalgesia following maternal separation [PDF]
Frontiers in PharmacologyBackgroundSress early in life has been linked to visceral hyperalgesia and associated functional gastrointestinal disorders. In a mouse model of visceral hyperalgesia, we investigated whether the EphB2 receptor and its EphrinB2 ligand in spinal cord ...
Shufen Guo +8 more
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Frontiers in Behavioral Neuroscience, 2021 Maternal separation has been shown to disrupt proper brain development and maturation, having profound consequences on the neuroendocrine systems in charge of the stress response, and has been shown to induce behavioral and cognitive abnormalities.
Sara Mejía-Chávez +4 more
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Early Life Stress Increases Metabolic Risk, HPA Axis Reactivity, and Depressive-Like Behavior When Combined with Postweaning Social Isolation in Rats. [PDF]
PLoS ONE, 2016 Early-life stress is associated with depression and metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. Such associations could be due to increased glucocorticoid levels.
Javier Vargas +3 more
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Epigenetic upregulation of corticotrophin-releasing hormone mediates postnatal maternal separation-induced memory deficiency. [PDF]
PLoS ONE, 2014 Accumulating evidences demonstrated that early postnatal maternal separation induced remarkable social and memory defects in the adult rodents. Early-life stress induced long-lasting functional adaptation of neuroendocrine hypothalamic-pituitary-adrenal ...
Aiyun Wang +6 more
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Examining the Factorial Structure of the Maternal Separation Anxiety Scale in a Portuguese Sample
Frontiers in Psychology, 2021 The increase in women’s labor market participation emphasizes the importance of understanding maternal separation anxiety, that is, the unpleasant maternal emotional state, due to the actual or anticipated short-term separation from the child. Drawing on
Maryse Guedes +4 more
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