Maternal Separation Modifies the Activity of Social Processing Brain Nuclei Upon Social Novelty Exposure [PDF]
Maternal separation has been shown to disrupt proper brain development and maturation, having profound consequences on the neuroendocrine systems in charge of the stress response, and has been shown to induce behavioral and cognitive abnormalities.
Sara Mejía-Chávez +4 more
doaj +4 more sources
Adverse early life experiences, such as maternal separation, are associated with an increased risk for several mental health problems. Symptoms induced by maternal separation that mirror clinically relevant aspects of mental problems, such as cognitive ...
Bo Ou-Yang +6 more
doaj +3 more sources
Maternal Separation Impairs Cocaine-Induced Behavioural Sensitization in Adolescent Mice. [PDF]
Adverse early-life conditions induce persistent disturbances that give rise to negative emotional states. Therefore, early life stress confers increased vulnerability to substance use disorders, mainly during adolescence as the brain is still developing.
Irene Gracia-Rubio +5 more
doaj +3 more sources
Maternal separation during breastfeeding as a risk factor for developing giardiasis: evaluation in a rodent model [PDF]
Background Giardia lamblia is a globally prevalent gastrointestinal parasite. Breastfeeding provides protective effects against infections, but the impact of early life stress, such as maternal separation, on G. lamblia infection remains unclear.
M. F. Gerena-Cruz +4 more
doaj +2 more sources
Genetic Regulation of Maternal Oxytocin Response and Its Influences on Maternal Behavior
We interrogated the genetic modulation of maternal oxytocin response and its association with maternal behavior using genetic risk scores within the oxytocin receptor (OXTR) gene.
Divya Mehta +6 more
doaj +2 more sources
Dissociative symptoms in school-aged adopted children who experienced maternal separation and disruptive caregiving in infancy [PDF]
Amounting findings on maternal separation and early disturbed caregiving suggest that this type of early experience negatively influences socioemotional development and may be associated with behavioral and mental health problems in later life ...
Petra Winnette +3 more
doaj +2 more sources
The impact of environmental factors during maternal separation on the behaviors of adolescent C57BL/6 mice [PDF]
Neonatal maternal separation is a widely used method to construct an early-life stress model in rodents. In this method, pups are separated from their mothers for several hours every day during the first 2 weeks of life, which results in adverse early ...
Sangyep Shin, Sukwon Lee
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Inheritable effect of unpredictable maternal separation on behavioral responses in mice
The long-term impact of early stress on behavior and emotions is well documented in humans, and can be modeled in experimental animals. In mice, maternal separation during early postnatal development induces poor and disorganized maternal care, and ...
Isabelle C Weiss +3 more
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The postpartum period is a sensitive time where women are especially vulnerable to develop postpartum depression (PPD), with 10%–15% of women affected. This review investigates whether the maternal separation (MS) paradigm in rodents holds the potential to help to understand mothers suffering from PPD.
Mundorf, Annakarina (Dr. rer. nat.) +2 more
openaire +2 more sources
The establishment of positive early parent–infant relationships provide essential nourishment and social stimulation for newborns. During the early stages of postnatal brain development, events such as synaptogenesis, neuronal maturation and glial ...
Yuan Zhang, Shu Wang, Mingyan Hei
doaj +2 more sources

