Maternal Separation Impairs Cocaine-Induced Behavioural Sensitization in Adolescent Mice. [PDF]
Adverse early-life conditions induce persistent disturbances that give rise to negative emotional states. Therefore, early life stress confers increased vulnerability to substance use disorders, mainly during adolescence as the brain is still developing.
Irene Gracia-Rubio +5 more
doaj +4 more sources
Genetic Regulation of Maternal Oxytocin Response and Its Influences on Maternal Behavior [PDF]
We interrogated the genetic modulation of maternal oxytocin response and its association with maternal behavior using genetic risk scores within the oxytocin receptor (OXTR) gene.
Divya Mehta +6 more
doaj +3 more sources
The postpartum period is a sensitive time where women are especially vulnerable to develop postpartum depression (PPD), with 10%–15% of women affected. This review investigates whether the maternal separation (MS) paradigm in rodents holds the potential to help to understand mothers suffering from PPD.
Mundorf, Annakarina (Dr. rer. nat.) +2 more
openaire +2 more sources
Maternal separation as early-life stress: Mechanisms of neuropsychiatric disorders and inspiration for neonatal care [PDF]
The establishment of positive early parent–infant relationships provide essential nourishment and social stimulation for newborns. During the early stages of postnatal brain development, events such as synaptogenesis, neuronal maturation and glial ...
Yuan Zhang, Shu Wang, Mingyan Hei
doaj +2 more sources
Combined Effect of Maternal Separation and Early-Life Immune Activation on Brain and Behaviour of Rat Offspring [PDF]
Adversity during early life, a critical period for brain development, increases vulnerability and can have a lasting impact on the brain and behaviour of a child.
Bharti Biswas +3 more
doaj +2 more sources
Activation of EphrinB2/EphB2 signaling in the spine cord alters glia-neuron interactions in mice with visceral hyperalgesia following maternal separation [PDF]
BackgroundSress early in life has been linked to visceral hyperalgesia and associated functional gastrointestinal disorders. In a mouse model of visceral hyperalgesia, we investigated whether the EphB2 receptor and its EphrinB2 ligand in spinal cord ...
Shufen Guo +8 more
doaj +2 more sources
Sensitive windows, sensitive outcomes: Early or late-postnatal maternal separation differentially impacts puberty and behavior. [PDF]
Balakrishnan A +3 more
europepmc +2 more sources
An enriched environment ameliorates the reduction of parvalbumin-positive interneurons in the medial prefrontal cortex caused by maternal separation early in life. [PDF]
Irie K +12 more
europepmc +3 more sources
Effects of maternal separation on punishment-driven risky decision making in adolescence and adulthood. [PDF]
Minnes GL +6 more
europepmc +3 more sources
Effects of Maternal Differentiation of Self, Maternal Separation Anxiety and Overprotective Parenting on Children’s Separation Anxiety [PDF]
Junghee Lee, Sae‐Young Han
openalex +2 more sources

