One-Week Maternal Separation Caused Sex-Specific Changes in Behavior and Hippocampal Metabolomics of Offspring Rats [PDF]
Brain SciencesTo investigate the effects of one-week maternal separation (MS) on anxiety- and depression-like behaviors in adolescent and adulthood as well as adult hippocampal metabolomics simultaneously in offspring female and male rats.
Meng-Chen Dong +6 more
doaj +2 more sources
Combined Effect of Maternal Separation and Early-Life Immune Activation on Brain and Behaviour of Rat Offspring [PDF]
BiomoleculesAdversity during early life, a critical period for brain development, increases vulnerability and can have a lasting impact on the brain and behaviour of a child.
Bharti Biswas +3 more
doaj +2 more sources
Activation of EphrinB2/EphB2 signaling in the spine cord alters glia-neuron interactions in mice with visceral hyperalgesia following maternal separation [PDF]
Frontiers in PharmacologyBackgroundSress early in life has been linked to visceral hyperalgesia and associated functional gastrointestinal disorders. In a mouse model of visceral hyperalgesia, we investigated whether the EphB2 receptor and its EphrinB2 ligand in spinal cord ...
Shufen Guo +8 more
doaj +2 more sources
Early Life Stress Increases Metabolic Risk, HPA Axis Reactivity, and Depressive-Like Behavior When Combined with Postweaning Social Isolation in Rats. [PDF]
PLoS ONE, 2016 Early-life stress is associated with depression and metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. Such associations could be due to increased glucocorticoid levels.
Javier Vargas +3 more
doaj +1 more source
Epigenetic upregulation of corticotrophin-releasing hormone mediates postnatal maternal separation-induced memory deficiency. [PDF]
PLoS ONE, 2014 Accumulating evidences demonstrated that early postnatal maternal separation induced remarkable social and memory defects in the adult rodents. Early-life stress induced long-lasting functional adaptation of neuroendocrine hypothalamic-pituitary-adrenal ...
Aiyun Wang +6 more
doaj +1 more source
Examining the Factorial Structure of the Maternal Separation Anxiety Scale in a Portuguese Sample
Frontiers in Psychology, 2021 The increase in women’s labor market participation emphasizes the importance of understanding maternal separation anxiety, that is, the unpleasant maternal emotional state, due to the actual or anticipated short-term separation from the child. Drawing on
Maryse Guedes +4 more
doaj +1 more source
Behavioral responses to cow and calf separation: separation at 1 and 100 days after birth [PDF]
Animal Bioscience, 2023 Objective The aim was to compare the behavioral response to full separation of cows and calves maintained together for 100 days or 24 h. Methods Twelve Holstein-Friesian cow-calf pairs were enrolled into either treatment or industry groups (n = 6 cow ...
Sarah E. Mac +2 more
doaj +1 more source
Maternal separation in rats induces neurobiological and behavioral changes on the maternal side [PDF]
Scientific Reports, 2020 AbstractThe time after parturition is a sensitive period for mothers where they are prone to develop psychopathological symptoms. Studies investigating dams after separation from their pups (maternal separation, MS) showed that MS induces alterations similar to postpartum depression.
Bölükbas, Ibrahim +2 more
openaire +4 more sources
IBRO Neuroscience Reports, 2022 Environmental stimuli in early life are recognized to affect brain development and behavior. Mother-pup interaction constitutes a determinant stimulus during this critical period.
Ada Sinani +5 more
doaj +1 more source
Biochemical and clinical diagnostic aspects of circulating nucleic acids [PDF]
, 2005 We investigated the size distribution of fetal DNA using a combination of agorose gel electrophoresis, Southern blot and real time PCR assay. Our results showed plasma DNA presents apoptotic characteristics and the cell free fetal DNA is generally ...
Li, Ying
core +1 more source