Results 81 to 90 of about 100,164 (294)

Application of deformity principles in the management of spinal neoplasms: A Primer

North American Spine Society Journal
: Background: With advances in surgical techniques, radiation, and systemic therapy, prognoses and quality of life have improved amongst patients with primary and metastatic vertebral column tumors.
Zach Pennington, MD, Joseph H Schwab, MD, Sheng-fu Larry Lo, MD MHS, C. Rory Goodwin, MD PhD, Matthew L Goodwin, MD PhD, Matthew Colman, MD, Raphaële Charest-Morin, MD, Nicolas Dea, MD, Daniel Lubelski, MD, Ali Ozturk, MD, Jacob M. Buchowski, MD MS, Wende Gibbs, MD, Wesley Hsu, MD, Ajit Krishnaney, MD, Ilya Laufer, MD, Mohamed Macki, MD, Addisu Mesfin, MD, Ganesh Shankar, MD PhD, Dan Tobert, MD, John Shin, MD MBA, Andrew Platt, MD, Daniel M Sciubba, MD MBA   +21 more
doaj   +1 more source

Adult Spinal Deformity: Current Concepts and Decision-Making Strategies for Management

Asian Spine Journal, 2020
Adult spinal deformity (ASD) is characterized by three-dimensional abnormalities of the thoracic or thoracolumbar spine that exerts significant impacts on the health-related quality of life (HRQoL).
Hong-Jin Kim, J. Yang, D. Chang, S. Suk, S. Suh, K. Song, Jong-Beom Park, Woojin Cho   +7 more
semanticscholar   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

Negative Sagittal Balance Following Adult Spinal Deformity Surgery

Global Spine Journal, 2018
Study Design: Retrospective cohort study. Objective: Elucidate negative sagittal balance following adult spinal deformity surgery. Methods: We conducted a retrospective review of adult spinal deformity patients who underwent long fusion (>5 levels) to ...
Robert K. Merrill BS, Jun S. Kim MD, Ian T. McNeill MD, Samuel C. Overley MD, James E. Dowdell MD, John M. Caridi MD, Samuel K. Cho MD   +6 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Cognitive Impairment following Adult Spinal Deformity Surgery

Global Spine Journal, 2016
Introduction Elderly patients undergoing major surgery may experience cognitive deterioration due to lesser plasticity in their brain tissue. This so called postoperative cognitive dysfunction (POCD) syndrome is characterized with non-specific ...
Vugar Nabiyev, Selim Ayhan, Selcem Yuksel, Tiro Mmopelwa, Montse Domingo Sabat, Ferran Pellise, Ahmet Alanay, Francisco Javier Sanchez Perez-Grueso, Frank Kleinstuck, Ibrahim Obeid, Emre Acaroglu,   +11 more
doaj   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Introduction. Adult spinal deformity [PDF]

Neurosurgical Focus, 2017
Shaffrey, Christopher I, Smith, Justin S, Ames, Christopher P, Yagi, Mitsuru, Alanay, Ahmet, Ha, Yoon   +5 more
openaire   +2 more sources