Results 91 to 100 of about 4,970 (302)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

An elderly female with adult-onset Still’s disease initially misdiagnosed as prosthetic joint infection after total knee arthroplasty: lessons in differential diagnosis and treatment

BMC Geriatrics, 2020
Background High fever, knee swelling and pain after knee arthroplasty are often considered as symptoms of acute prosthetic joint infection. However, similar symptoms can also present as primary manifestations of adult-onset Still’s disease, which creates
Xufeng Jiao, Zheng Li, Shuai An, Jiang Huang, Guangzhong Yang, Yi Zhao, Jianghua Shen, Yanqi Chu, Charlie C. Yang, Guanglei Cao   +9 more
doaj   +1 more source

Acute liver transplantation in a 41-year-old male patient presenting symptoms of adult-onset Still's disease [PDF]

, 2011
L
Andrès E., Bywaters E.G., Coffernils M., Cush J.J., Fautrel B., Ishikawa M., Kadar J., Linde B., Mehrpoor G., Mert A., Motoo Y., Nemes B., Nemes B., Nemes B., Ogata A., Singh S., Still G.F., Taccone F.S., Takami A., Teran A., Yamaguchi M., Zhu G.   +21 more
core   +2 more sources

[Myocardiopericarditis in adult still's disease]. [PDF]

Arch Peru Cardiol Cir Cardiovasc, 2023
Horna N M, Romero R, Larrauri C, Córdova F, Martín Mispireta J, Alarcón J.   +5 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Cryoglobulinemia vasculitis associated with adult‐onset Still's disease

Clinical Case Reports
Key Clinical Message The present case indicates that cryoglobulinemia vasculitis should be considered in the differential diagnosis of purpura in patients with adult‐onset Still's disease (AOSD).
Noriharu Nakagawa, Ai Fujii, Yoshimichi Ueda, Masahide Yamazaki   +3 more
doaj   +1 more source

Severe Adult Still's Disease Complicated by Purtscher-Like Retinopathy Treated with Intravenous Pulse Methylprednisolone and Tocilizumab. [PDF]

Case Rep Ophthalmol, 2021
Akiyama K, Iwasaki Y, Tanaka R.
europepmc   +1 more source

Elevated liver enzymes in inflammatory bowel disease: the role and safety of infliximab [PDF]

, 2016
BACKGROUND: Abnormal liver enzymes are frequently encountered in inflammatory bowel disease (IBD) patients. Infliximab has been implicated in inducing drug-induced liver injury, autoimmune hepatitis or reactivation of hepatitis B virus.
Burroughs, AK, Epstein, O, Hamilton, M, Manousou, P, Murray, C, O'Beirne, J, Parisi, I, Rossi, RE, Theocharidou, E, Tsochatzis, E   +9 more
core