Results 101 to 110 of about 4,997 (303)
Severe Adult Still's Disease Complicated by Purtscher-Like Retinopathy Treated with Intravenous Pulse Methylprednisolone and Tocilizumab. [PDF]
Case Rep Ophthalmol, 2021 Akiyama K, Iwasaki Y, Tanaka R.
europepmc +1 more source
Juvenile Rheumatoid Arthritis: Early Diagnosis, Management, and Prognosis [PDF]
, 1974 Rheumatoid arthritis (RA) is the major chronic rheumatic disorder of childhood.
Calabro, John J.
core +1 more source
Anakinra for the treatment of adult-onset Still's disease [PDF]
, 2018 : Introduction: Adult onset Still's disease (AOSD) is an uncommon systemic inflammatory disease on the clinical spectrum of autoinflammatory disorders.
Atienza Mateo, Belén +4 more
core +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
EULAR Rheumatology Open: Objectives: Adult-onset Still’s disease presents with nonspecific and heterogeneous features. This study aims to elucidate the development of initial symptoms and their relationship with the disease course in adult-onset Still’s disease.
Hiroya Tamai +3 more
doaj +1 more source
Venous Thromboembolism Secondary to Adult-Onset Still’s Disease: a Case Report
Journal of Cardiovascular Emergencies, 2018 A 56-year-old man presented to the emergency department with pain, swelling, and restricted mobility of the left lower limb and shortness of breath on exertion in the previous 3 days.
Calborean Veronica +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Enfermedad de Still - Diagnóstico infregente en la Edad Vieja
Galicia Clínica, 2019 Adult Still's Disease is a rare systemic inflammatory disease. It is characteristically identified in the young adult, with few cases described in older patients. The aetiology and pathogenesis remain unknown. The absence of uniformly accepted diagnostic
Ana Nogueira +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source