Results 91 to 100 of about 4,997 (303)

Adult Onset Still’s Disease: A Case Report with a Rare Clinical Manifestation and Pathophysiological Correlations

open access: yesCase Reports in Medicine, 2013
Adult-onset Still’s disease is an inflammatory multisystemic disease of unknown etiology. Pleuritis is the most common pulmonary manifestation and pleural effusions are usually exudates with a predominance of neutrophils.
Katerina M. Antoniou   +6 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Adult Still’s Disease

open access: yes, 2011
1. The clinical features of adult Still’s disease resemble the systemic form of JRA a. Seronegative chronic polyarthritis associated with a systemic inflammatory illness b. Initially described in 1897 by George F. Still (pathologist) c. Subsequently detailed in adults in 1971 by Eric Bywaters 2. Epidemiology a. Rare b.
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

An elderly female with adult-onset Still’s disease initially misdiagnosed as prosthetic joint infection after total knee arthroplasty: lessons in differential diagnosis and treatment

open access: yesBMC Geriatrics, 2020
Background High fever, knee swelling and pain after knee arthroplasty are often considered as symptoms of acute prosthetic joint infection. However, similar symptoms can also present as primary manifestations of adult-onset Still’s disease, which creates
Xufeng Jiao   +9 more
doaj   +1 more source

[Myocardiopericarditis in adult still's disease]. [PDF]

open access: yesArch Peru Cardiol Cir Cardiovasc, 2023
Horna N M   +5 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Cryoglobulinemia vasculitis associated with adult‐onset Still's disease

open access: yesClinical Case Reports
Key Clinical Message The present case indicates that cryoglobulinemia vasculitis should be considered in the differential diagnosis of purpura in patients with adult‐onset Still's disease (AOSD).
Noriharu Nakagawa   +3 more
doaj   +1 more source

ADULT-ONSET STILL'S DISEASE TODAY

open access: yesНаучно-практическая ревматология, 2017
The lecture gives an update on adult-onset Still's disease, including that on the specific features of the clinical picture and treatment of this disease.
Yu. V. Muravyev, V. V. Lebedeva
doaj   +1 more source

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