Results 101 to 110 of about 4,970 (302)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
EULAR Rheumatology Open: Objectives: Adult-onset Still’s disease presents with nonspecific and heterogeneous features. This study aims to elucidate the development of initial symptoms and their relationship with the disease course in adult-onset Still’s disease.
Hiroya Tamai +3 more
doaj +1 more source
Venous Thromboembolism Secondary to Adult-Onset Still’s Disease: a Case Report
Journal of Cardiovascular Emergencies, 2018 A 56-year-old man presented to the emergency department with pain, swelling, and restricted mobility of the left lower limb and shortness of breath on exertion in the previous 3 days.
Calborean Veronica +3 more
doaj +1 more source
Enfermedad de Still - Diagnóstico infregente en la Edad Vieja
Galicia Clínica, 2019 Adult Still's Disease is a rare systemic inflammatory disease. It is characteristically identified in the young adult, with few cases described in older patients. The aetiology and pathogenesis remain unknown. The absence of uniformly accepted diagnostic
Ana Nogueira +2 more
doaj +1 more source
Juvenile Rheumatoid Arthritis: Early Diagnosis, Management, and Prognosis [PDF]
, 1974 Rheumatoid arthritis (RA) is the major chronic rheumatic disorder of childhood.
Calabro, John J.
core +1 more source
Anakinra for the treatment of adult-onset Still's disease [PDF]
, 2018 : Introduction: Adult onset Still's disease (AOSD) is an uncommon systemic inflammatory disease on the clinical spectrum of autoinflammatory disorders.
Atienza Mateo, Belén +4 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Laparoscopic transabdominal preperitoneal repair for inguinal hernia in a patient with an adult Still's disease receiving anti-interleukin-6 receptor monoclonal antibody therapy. [PDF]
J Surg Case Rep, 2022 Mimatsu K, Kamitaki Y, Fukino N.
europepmc +1 more source