Results 51 to 60 of about 4,997 (303)

Defective iron supply for erythropoiesis and adequate endogenous erythropoietin production in the anemia associated with systemic-onset juvenile chronic arthritis. [PDF]

, 1996
peer reviewedSystemic-onset juvenile chronic arthritis (SoJCA) is associated with high levels of circulating interleukin-6 (IL-6) and is frequently complicated by severe microcytic anemia whose pathogenesis is unclear.
Barosi, G., Beguin, Yves, Cazzola, M., de Benedetti, F., Invernizzi, R., Martini, A., Ponchio, L., Ravelli, A., Rosti, V.   +8 more
core   +1 more source

Derivation and validation of four patient clusters in Still's disease, results from GIRRCS AOSD-study group and AIDA Network Still Disease Registry [PDF]

, 2023
Background Different patient clusters were preliminarily suggested to dissect the clinical heterogeneity in Still's disease. Thus, we aimed at deriving and validating disease clusters in a multicentre, observational, prospective study to stratify these ...
Alibaz-Oner F., Almaghlouth I. A., Antonelli I. P. D. B., Asfina K., Atzeni F., Bartoloni E., Berardicurti O., Bugatti S., Caggiano V., Cantarini L., Carubbi F., Caso F., Ciccia F., Cipriani P., Costa L., Dagna L., De Stefano L., Del Giudice E., Di Cola I., Di Muzio C., Direskeneli H., Emmi G., Erten S., Fabiani C., Fotis L., Frediani B., Giacomelli R., Giardini H., Gidaro A., Govoni M., Guggino G., Hernandez-Rodriguez J., Hinojosa-Azaola A., Iacono D., Iagnocco A., La Torre F., Lo Gullo A., Lopalco G., Maggio M. C., Maier A., Makowska J., Martin-Nares E., Masedu F., Mauro D., Montecucco C., Monti S., Navarini L., Ogunjimi B., Pantano I., Perosa F., Prete M., Ragab G., Rossi S., Ruscitti P., Sevik G., Sfikakis P. P., Sfriso P., Simonini G., Tharwat S., Torres-Ruiz J., Tufan A., Valenti M., Vitale A.   +62 more
core   +1 more source

Adult-Onset Still Disease (AOSD) [PDF]

The Journal of the American Board of Family Medicine, 2010
Adult-onset Still disease (AOSD) is an uncommon clinical entity that predominantly affects young adults. One of the most common presentations of the disease is fever of unknown origin. Early diagnosis can be difficult because fever of unknown origin is more commonly seen with other conditions such as malignancy or infection.
Egambaram, Senthilvel, Aphrodite, Papadakis, Michael, McNamara, Iyabode, Adebambo   +3 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Noncaseating suppurative granulomatous lymphadenitis in adult onset Still’s disease – a diagnostic dilemma in a tuberculosis-endemic region: a case report

Journal of Medical Case Reports, 2018
Background Lymphadenopathy is not an uncommon presentation of adult onset Still’s disease: it is present in up to two thirds of patients with adult onset Still’s disease.
S. W. G. J. W. Chinthaka, R. L. Satarasinghe, S. Senanayake, W. A. P. S. R. Weerarathne, A. A. M. Anfaz, M. P. Deraniyagala   +5 more
doaj   +1 more source

Molecular mechanisms in idiopathic inflammatory myopathies [PDF]

, 2014
Background: Myositis is a group of rare autoimmune diseases. Muscle weakness and fatigue are the dominant symptoms and inflammation with T cells and macrophages is a characteristic finding in muscle tissue.
Zong, Mei
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Macrophage Activation Syndrome Associated with Adult-Onset Still’s Disease Successfully Treated with Anakinra

Case Reports in Rheumatology, 2016
Macrophage activation syndrome (MAS) is a potentially fatal complication of Adult-Onset Still’s disease (Still’s disease). Whereas an increasing body of evidence supports interleukin-1 (IL-1) blockade as a promising treatment for Still’s disease, whether
Aswini Kumar, Hiroshi Kato
doaj   +1 more source

The CD68+/H-ferritin+ cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular level of H-ferritin in the same tissue: Correlation with disease severity and implication for pathogenesis [PDF]

, 2015
In this work, we aimed to evaluate the levels of ferritin enriched in H subunits (H-ferritin) and ferritin enriched in L subunits (L-ferritin) and the cells expressing these two molecules in the lymph node (LN) biopsies obtained from adult-onset Still's ...
Berardicurti, O., Carubbi, F., CICCIA, Francesco, Cipriani, P., Di Benedetto, P., Giacomelli, R., GUGGINO, Giuliana, Liakouli, V., Rizzo, A., Ruscitti, P., TRIOLO, Giovanni   +10 more
core   +1 more source

BARTONELLA ENDOCARDITIS MIMICKING ADULT STILL’S DISEASE [PDF]

Acta Clinica Belgica, 2008
We describe the case of a 39-year-old Caucasian woman who was admitted to the University Hospital of Antwerp with a clinical picture suggestive of adult Still's disease. Even though a transoesophageal echocardiography showed endocarditis of the aortic valve, blood cultures remained negative. Additional serological testing revealed a positive result for
De Clerck, K. F., Van Offel, J. F., Vlieghe, E., Van Marck, E., Stevens, W. J.   +4 more
openaire   +3 more sources