Results 91 to 100 of about 9,751,042 (392)

Gangliogliomas in adults [PDF]

open access: yesCancer, 1997
Gangliogliomas are rare tumors occurring in both children and adults that are characterized by the presence of neoplastic cells resembling both neurons and glia.The authors reviewed 18 adults patients with intracranial gangliogliomas treated at the study institutions between October 1987 and November 1995.The median age at diagnosis was 33.7 years ...
Douglas C. Anthony   +3 more
openaire   +3 more sources

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Prognostic significance of delirium subtypes in critically ill medical and surgical patients: a secondary analysis of a prospective multicenter study

open access: yesJournal of Intensive Care, 2022
Background The prognostic implication of delirium subtypes in critically ill medical and surgical patients is scarcely investigated. The objective was to determine how delirium subtypes are associated with hospital mortality and other clinical outcomes ...
Lisa Smit   +6 more
doaj   +1 more source

Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association.

open access: yesMedicine & Science in Sports & Exercise, 2007
OBJECTIVE To issue a recommendation on the types and amounts of physical activity needed to improve and maintain health in older adults. PARTICIPANTS A panel of scientists with expertise in public health, behavioral science, epidemiology, exercise ...
M. Nelson   +7 more
semanticscholar   +1 more source

Icebreakers for Adults

open access: yesEDIS, 2020
Building rapport is key when creating a team culture. As groups change over time, it is imperative to continually reintroduce and reacclimate new team members to long-standing teammates. Leaders of groups that undergo constant change, like those whose jobs involve volunteers, may find it challenging to find innovative ways to bring people together ...
Megan Stein, Taylor Nash
openaire   +5 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults

open access: yesCirculation, 2013
Loria, Barbara E. Millen, Cathy A. Nonas, F. Xavier Pi-Sunyer, June Stevens, Victor J. Stevens, Karen A. Donato, Frank B. Hu, Van S. Hubbard, John M. Jakicic, Robert F. Kushner, Catherine M. Michael D. Jensen, Donna H. Ryan, Caroline M.
M. Jensen   +40 more
semanticscholar   +1 more source

Health System Performance for the High-Need Patient: A Look at Access to Care and Patient Care Experiences [PDF]

open access: yes, 2016
Achieving a high-performing health system will require improving outcomes and reducing costs for high-need, high-cost patients—those who use the most health care services and account for a disproportionately large share of health care spending.
Claudia A. Salzberg   +6 more
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

The prevalence of comorbid depression in adults with diabetes: a meta-analysis.

open access: yesDiabetes Care, 2001
OBJECTIVE To estimate the odds and prevalence of clinically relevant depression in adults with type 1 or type 2 diabetes. Depression is associated with hyperglycemia and an increased risk for diabetic complications; relief of depression is associated ...
Ryan J. Anderson   +3 more
semanticscholar   +1 more source

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