Results 81 to 90 of about 10,055,911 (359)

ACG Clinical Guideline: Ulcerative Colitis in Adults

open access: yesAmerican Journal of Gastroenterology, 2019
Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the preferred approach to the management of adults with UC and represent the official practice recommendations of the American College of Gastroenterology.
D. Rubin   +4 more
semanticscholar   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Older Adults’ Social Relations: Life Satisfaction to Widowhood [PDF]

open access: yes, 2018
The objective of this study was to examine the breadth and depth of relationships with relatives and friends and the possible implications of those relationships with regards to life satisfaction to widowhood.
Ahn, Bonnie, Kang, Hyunsook
core   +1 more source

The relationship between attentional processing of emotional information and personality : a comparison between older and younger adults [PDF]

open access: yes, 2019
Older adults have been found to focus more on positive and less on negative information compared to younger adults. Yet, results on this attentional positivity effect are inconsistent.
De Raedt, Rudi   +3 more
core   +2 more sources

Tobacco Product Use Among Adults — United States, 2019

open access: yesMMWR. Morbidity and mortality weekly report, 2020
Cigarette smoking remains the leading cause of preventable disease and death in the United States (1). The prevalence of current cigarette smoking among U.S.
M. Cornelius   +4 more
semanticscholar   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

An integrative review of adult patient-reported reasons for non-urgent use of the emergency department [PDF]

open access: gold, 2023
Amanda McIntyre   +4 more
openalex   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Ectopic pregnancy treatment by combination therapy

open access: yesOpen Medicine, 2016
Detectability of early stages of ectopic pregnancies has increased due to improvements in ultrasonographic and biochemical techniques. Since the patients’ future procreative plans must be taken into consideration when commencing treatment, the goal of ...
Cymbaluk-Płoska Aneta   +3 more
doaj   +1 more source

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