Results 81 to 90 of about 5,977,231 (321)
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
Kształcenie ustawiczne we współczesnych strategiach zrównoważonego rozwoju
Ze względu na plastyczność i dynamikę współczesnego życia społeczno-kulturowego można zauważyć, że edukacja przedstawia się obecnie jako system otwarty, tzn. taki, w ramach którego nie da się zaproponować pewnych stałych i niezmiennych rozwiązań. Zdaniem
Oksana Voitovska+2 more
doaj +1 more source
Computational Models of Adult Neurogenesis [PDF]
Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the context of and adult brain. Here we propose two models where new projection neurons are incorporated.
arxiv +1 more source
Taking Stock of the Present and Future of Smart Technologies for Older Adults and Caregivers [PDF]
Technology has the opportunity to assist older adults as they age in place, coordinate caregiving resources, and meet unmet needs through access to resources. Currently, older adults use consumer technologies to support everyday life, however these technologies are not always accessible or as useful as they can be.
arxiv
The prevalence of comorbid depression in adults with diabetes: a meta-analysis.
OBJECTIVE To estimate the odds and prevalence of clinically relevant depression in adults with type 1 or type 2 diabetes. Depression is associated with hyperglycemia and an increased risk for diabetic complications; relief of depression is associated ...
Ryan J. Anderson+3 more
semanticscholar +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Melorheostosis: a rare entity: a case report
Melorheostosis is a rare entity belonging to the group of sclerotic bone dysplasias. Described for the first time in 1922 by Leri, it remains imperfectly known as clinical presentations are highly variable, and the etiological diagnosis is not fully ...
Abdelhakim Kherfani, Hachem Mahjoub
doaj +1 more source
Older Adults and Voice Interaction: A Pilot Study with Google Home [PDF]
In this paper we present the results of an exploratory study examining the potential of voice assistants (VA) for some groups of older adults in the context of Smart Home Technology (SHT). To research the aspect of older adults' interaction with voice user interfaces (VUI) we organized two workshops and gathered insights concerning possible benefits ...
arxiv +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez+3 more
wiley +1 more source