Results 81 to 90 of about 9,751,042 (392)

Gait speed and survival in older adults.

Journal of the American Medical Association (JAMA), 2011
CONTEXT Survival estimates help individualize goals of care for geriatric patients, but life tables fail to account for the great variability in survival.
S. Studenski, S. Perera, K. Patel, C. Rosano, K. Faulkner, M. Inzitari, J. Brach, J. Chandler, Peggy Cawthon, E. B. Connor, M. Nevitt, M. Visser, S. Kritchevsky, Stefania Badinelli, T. Harris, A. Newman, J. Cauley, L. Ferrucci, J. Guralnik   +18 more
semanticscholar   +1 more source

The effects of Tai Chi on peripheral somatosensation, balance, and fitness in Hispanic older adults with type 2 diabetes:a pilot and feasibility study [PDF]

, 2015
Peripheral neuropathy and loss of somatosensation in older adults with type 2 diabetes can increase risk of falls and disability. In nondiabetic older adult population Tai Chi has been shown to enhance balance and fitness through improvements in ...
Cavegn, Elisabeth I., Riskowski, Jody
core   +4 more sources

Walking to the beat of their own drum: how children and adults meet timing constraints [PDF]

, 2015
Walking requires adapting to meet task constraints. Between 5- and 7-years old, children's walking approximates adult walking without constraints. To examine how children and adults adapt to meet timing constraints, 57 5- to 7-year olds and 20 adults ...
Gill, Simone V.
core   +6 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults — United States, 2016

MMWR. Morbidity and mortality weekly report, 2018
Chronic pain, one of the most common reasons adults seek medical care (1), has been linked to restrictions in mobility and daily activities (2,3), dependence on opioids (4), anxiety and depression (2), and poor perceived health or reduced quality of life
James M. Dahlhamer, J. Lucas, C. Zelaya, R. Nahin, S. Mackey, L. DeBar, Robert W Kerns, M. Von Korff, L. Porter, C. Helmick   +9 more
semanticscholar   +1 more source

Pancreatoblastoma in an adult

Indian Journal of Pathology and Microbiology, 2015
Pancreatoblastoma is a malignant pancreatic tumor that rarely occurs in adults. We report a case of an adult female with pancreatoblastoma. A mass was detected in the pancreatic head using computed tomography and ultrasonography. The clinical diagnosis was a solid-pseudopapillary neoplasm of the pancreas.
Na Tang, Enhua Wang, Di Zhang, Yang Liu
openaire   +4 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Predicting the probability for falls in community-dwelling older adults using the Timed Up & Go Test.

Physical Therapy, 2000
BACKGROUND AND PURPOSE This study examined the sensitivity and specificity of the Timed Up & Go Test (TUG) under single-task versus dual-task conditions for identifying elderly individuals who are prone to falling. SUBJECTS Fifteen older adults with no
A. Shumway-cook, Sandy Brauer, M. Woollacott   +2 more
semanticscholar   +1 more source