Results 141 to 150 of about 7,176,180 (262)
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source
Advance care planning in practice : everybody's business
Mullick and colleagues provide an excellent overview of advance care planning, an area of practice that is rapidly growing in relevance and importance.1 They focus on three main tools for advance care planning.
Mitchell, Sarah J., Dale, Jeremy
core
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song +10 more
wiley +1 more source
Service Evaluation of an Advance Care Plan Tool [PDF]
Following the successful bid for a Department of Health grant in October 2010, the Kent and Medway Children and Young People’s (KMCYP) Palliative Care Network ran a six month project to raise the awareness of children’s palliative care.
Holdsworth, Laura M., Billings, Jenny R.
core
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
Decisions regarding health care are increasingly difficult to make, especially as patients live longer and with more medical comorbidities. The case of Al Barnes, a man with advanced dementia who recently died in a Minnesota hospital despite months of ...
Mueller, Paul S +2 more
core
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini +12 more
wiley +1 more source
Advance Care Planning in Rural Primary Care Practice: A Quality Improvement Project
Advance care directives outline the care decisions family and providers are to follow in end of life care. End of life care is often a topic that patients and providers do not typically spend time discussing.
Olson, Naomi
core
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source

