Results 121 to 130 of about 115,454 (309)

Advance Care Planning and Hospice Enrollment: Who Really Makes the Decision to Enroll? [PDF]

open access: yes, 2010
PURPOSE: The purpose of this study was to assess patient participation in advance care planning (ACP) and the decision to enroll in hospice. METHODS: One hundred sixty-five family members of patients who died in hospice between January 2004 and September
Kapo, Jennifer M   +3 more
core   +1 more source

The care planning umbrella: The evolution of advance care planning

open access: yesJournal of the American Geriatrics Society, 2023
Susan E. Hickman   +4 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The Realist Evaluation of a Palliative Integrated Care Pathway in Primary Care: What Works, For Whom and in What Circumstances? [PDF]

open access: yes, 2014
Background: Finding effective ways to care for people with palliative care needs is a national priority. A primary care locality has developed and implemented an Integrated Care Pathway (ICP) for those with life limiting illnesses.
Dalkin, Sonia
core  

Patient perceptions of advance care planning within primary care: a systematic review of facilitators and barriers

open access: yesBMC Primary Care
Background Advance care planning is a key aspect of palliative care and aims to establish patient preferences for future care, benefiting patients and their families.
Elizabeth Abbey   +4 more
doaj   +1 more source

Views of health care professionals on the implementation of preoperative advance care planning in older patients with head and neck cancer: Q methodology

open access: yesInternational Journal of Nursing Sciences
Objective: To investigate the views of health care professionals in a head and neck surgical department toward the implementation of advance care planning prior to surgery for older patients with head and neck cancer.
Huixian Yang   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

End of Life Care: A Quality Improvement Project [PDF]

open access: yes, 2018
Today people are living much longer lives with life expectancy at 78.8 years old and developing multiple chronic illnesses, which account for 7 out of 10 deaths per year.
Cranston, Shelby
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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