Results 111 to 120 of about 115,454 (309)
Surrogate Decision-Making and the Need for Advance Care Planning: Issues Raised by the Al Barnes Case [PDF]
, 2011 Decisions regarding health care are increasingly difficult to make, especially as patients live longer and with more medical comorbidities. The case of Al Barnes, a man with advanced dementia who recently died in a Minnesota hospital despite months of ...
Mueller, Paul S +2 more
core
Factors That Influence the Participation of Healthcare Professionals in Advance Care Planning for Patients With Terminal Cancer: A Nationwide Survey in Taiwan [PDF]
, 2010 A nationwide study was undertaken to investigate participation in advance care planning (ACP) by cancer care professionals following the enactment of the Natural Death Act in Taiwan in 2000.
Peng, Jen-Kuei Chen, Ching-Yu +4 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Negotiating Uncertainty: Advance care planning in advanced chronic obstructive pulmonary disease (COPD) [PDF]
, 2012 Physical and psychosocial symptoms in advanced chronic obstructive pulmonary disease (COPD) are cumulative and profound; global financial and human costs are huge.
Simpson, Anna Catherine
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Advance care planning and dementia: whose decision? [PDF]
, 2018 In this review of 25 papers the majority of data gathered by studies was largely retrospective involving surveys, documentary analysis of patient records and interviews with families, clinicians or those directly involved in a patient’s end of life care.
Jones, Kerry
core
Palliative Care and Social PracticeBackground: A majority of Japanese care managers lack medical qualifications, feel uncomfortable discussing future medical choices and believe that it is not their responsibility.
Shozo Okochi +11 more
doaj +1 more source
Revista Colombiana de Bioética, 2018 Advance Directives are grounded on the principles of respect for autonomy and beneficence. They are recommended in order to facilitate better health decision-making at the end of life. In Chile, they are not legally recognised, and there
Mariana Dittborn Bellalta
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source