Results 191 to 200 of about 181,542 (334)

Unpacking the psychiatric advance directive in low-resource settings: an exploratory qualitative study in Tamil Nadu, India [PDF]

open access: gold, 2013
Laura Shields   +5 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

[Advance Directives in Geriatrics: Proposed Management Algorithm]. [PDF]

open access: yesRev Med Inst Mex Seguro Soc
Anica-Malagón ED   +2 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

The role of specialized outpatient palliative care in emergency advance directives: fewer hospitalizations, greater alignment with patient wishes. [PDF]

open access: yesScand J Trauma Resusc Emerg Med
Batzler YN   +10 more
europepmc   +1 more source

Application of United States Advance Directives on Italian Soil [PDF]

open access: bronze, 1997
Mary Lois Kinney   +2 more
openalex   +1 more source

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

AWARENESS OF ADVANCE CARE PLANNING AND ADVANCE DIRECTIVE AMONG OLDER ADULTS IN JAPAN, HONG KONG, AND KOREA [PDF]

open access: gold, 2018
Aki Kawakami   +6 more
openalex   +1 more source

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