Unpacking the psychiatric advance directive in low-resource settings: an exploratory qualitative study in Tamil Nadu, India [PDF]
Laura Shields +5 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
[Advance Directives in Geriatrics: Proposed Management Algorithm]. [PDF]
Anica-Malagón ED +2 more
europepmc +1 more source
Associations between Latino ethnicity and the use of emotional support and completion of advance directives. [PDF]
Shen MJ, Prigerson HG, Maciejewski PK.
europepmc +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
The role of specialized outpatient palliative care in emergency advance directives: fewer hospitalizations, greater alignment with patient wishes. [PDF]
Batzler YN +10 more
europepmc +1 more source
Application of United States Advance Directives on Italian Soil [PDF]
Mary Lois Kinney +2 more
openalex +1 more source
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
AWARENESS OF ADVANCE CARE PLANNING AND ADVANCE DIRECTIVE AMONG OLDER ADULTS IN JAPAN, HONG KONG, AND KOREA [PDF]
Aki Kawakami +6 more
openalex +1 more source

