Results 201 to 210 of about 184,737 (335)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Advance Directives and Surrogate Decision Making in Health Care. United States, Germany and Japan [PDF]

, 2000
Ann Sommerville
openalex   +1 more source

Prevalence and Implementation of Psychiatric Advance Directives Among Veterans With Serious Mental Illness. [PDF]

Psychiatr Res Clin Pract
McBride L, Putris N, Hagans W, Hoxey A, Oakes D, Girard V, Avila A, Treichler E.   +7 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

203 EXPLORING PATIENTS UNDERSTANDING OF ADVANCE HEALTHCARE DIRECTIVES: A SNAPSHOT FROM A CARE OF THE OLDER PERSON ASSESSMENT UNIT [PDF]

, 2016
Anne Shekleton, Dzulkarnain Khalil, Bláithín Ní Bhuachalla, Mian Basit, Martin Mulroy, Olwyn Lynch   +5 more
openalex   +1 more source

Needs of key stakeholders to make advance care plans and advance directives for people with dementia: a scoping review. [PDF]

BMC Geriatr
Vinay R, Ferrario A, Gloeckler S, Biller-Andorno N.   +3 more
europepmc   +1 more source

Perceptions, Attitudes, and Knowledge toward Advance Directives: A Scoping Review. [PDF]

Healthcare (Basel), 2023
Macedo JC, Rego F, Nunes R.
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

New research on psychiatric advance directives

BMC Psychiatry, 2007
Elbogen Eric, Swanson Jeffrey, Swartz Marvin   +2 more
doaj   +1 more source

Rip Currents: Rough Water for End of Life Decision Making [PDF]

, 2017
Cerminara, Kathy L
core   +2 more sources