Results 201 to 210 of about 1,191,211 (370)

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Advance directives completion and hospital out-of-pocket expenditures. [PDF]

J Hosp Med, 2022
Zhu Y, Enguidanos S.
europepmc   +1 more source

Adherence to advance directives in critical care decision making: vignette study [PDF]

, 2003
Trevor Thompson
openalex   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Navigating Dementia and Delirium: Balancing Identity and Interests in Advance Directives. [PDF]

Nurs Philos
Rutenkröger M.
europepmc   +1 more source

[What do health care professionals know about advance directives?] [PDF]

Dtsch Med Wochenschr, 2023
Fleischmann C, Henking T, Schuler M, Neuderth S.   +3 more
europepmc   +1 more source

Advance directives are open to different interpretations [PDF]

, 2003

openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Health Care Advance Directives: The Next Generation [PDF]

, 1995
Whitton, Linda S.
core   +2 more sources

[Knowledge and misconceptions on advance directives-results of a citizen survey]. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2023
Fleischmann C, Henking T, Neuderth S.
europepmc   +1 more source