Results 101 to 110 of about 2,788,838 (297)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Blow-up of solutions to some differential equations and inequalities with shifted arguments

open access: yesElectronic Journal of Differential Equations, 2016
Using the test function technique, we obtain sufficient conditions for the blow-up of solutions to some differential equations and inequalities with advanced and delayed arguments, and for systems. Also we obtain upper estimates for the blow-up time.
Olga Salieva
doaj  

Constitutional Arguments: Interpretation and Legitimacy in Canadian Constitutional Thought

open access: yesOsgoode Hall Law Journal, 1989
The author provides an analysis and critique of the various types of arguments advanced by Canadian constitutional jurists to establish formal grounds for the legitimacy of judicial review under the Canadian constitution.
Joel C. Bakan
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Method of Coupled Fixed Points and Coupled Quasisolutions When Working with ODE’s with Arguments of Bounded Variation

open access: yesAbstract and Applied Analysis, 2013
The aim of this paper is to show the use of the coupled quasisolutions method as a useful technique when dealing with ordinary differential equations with functional arguments of bounded variation.
Rubén Figueroa
doaj   +1 more source

How to Do Things with Documents

open access: yesRivista di Estetica, 2012
This essay is a contribution to social ontology, drawing on the work of John Searle and of Hernando de Soto. At the center of the argument is the proposition advanced by De Soto in his Mystery of Capital to the effect that many of the entities which ...
Barry Smith
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Convergence and Divergence of the Solutions of a Neutral Difference Equation

open access: yesJournal of Applied Mathematics, 2011
We investigate the asymptotic behavior of the solutions of a neutral type difference equation of the form Δ[𝑥(𝑛)+𝑐𝑥(𝜏(𝑛))]+𝑝(𝑛)𝑥(𝜎(𝑛))=0, where 𝜏(𝑛) is a general retarded argument, 𝜎(𝑛) is a general deviated argument (retarded or advanced), 𝑐∈ℝ, (𝑝(𝑛))𝑛 ...
G. E. Chatzarakis, G. N. Miliaras
doaj   +1 more source

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