Results 221 to 230 of about 5,496,645 (302)

CA 15.3, Metastatic Burden, and Overall Survival in Hormone Receptor-Positive/HER2-Negative Advanced Breast Cancer: Real-World Evidence from Peru. [PDF]

Biomedicines
Valencia G, Rioja P, Meza J, Saavedra A, Castillo C, Sánchez A, Mantilla R, Bravo J, Gomez HL, Heredia M, Peralta O, Chirito M, Rabanal C, Aliaga K, Morante Z, Muñante B, Fuentes H, Munive C, Castañeda C, Neciosup S, Vidaurre T.   +20 more
europepmc   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Imlunestrant with or without abemaciclib in advanced breast cancer: safety analyses from the EMBER-3 trial. [PDF]

NPJ Breast Cancer
O'Shaughnessy J, Bidard FC, Neven P, Casalnuovo ML, Aftimos P, Saura C, Harbeck N, Carey LA, Curigliano G, Garcia-Saenz JA, Abad MF, Paula L, Park YH, Ozyilkan O, Munoz M, Barrett E, Cao S, Chawla A, Jhaveri KL.   +18 more
europepmc   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source

Black Hole Quencher‐Enhanced Plasmonic Photothermal Conversion

Advanced Science, EarlyView.
Researchers have developed a universal method to boost plasmonic photothermal conversion by attaching black hole quencher (BHQ) molecules to matched metal nanostructures. This hybrid approach increases efficiency by roughly threefold, reaching up to 69.1% in the near‐infrared‐II window.
Ruiyuan Zhang, Xinru Chen, Lin Shen, Jin Li   +3 more
wiley   +1 more source

Efficacy and Safety of Dalpiciclib in HR-Positive Advanced Breast Cancer: A Two-Center Retrospective Study. [PDF]

Cancers (Basel)
Li J, Zong Z, Zhu D, Xu X, Yan Y, Li J, Li F, Hao J.   +7 more
europepmc   +1 more source

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

Advanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen, Mengyuan Li, Lin Hou, Bin Yin, Boqin Qiang, Ran Gao, Pengcheng Shu, Xiaozhong Peng   +7 more
wiley   +1 more source

The effect of acceptance and commitment therapy on communication avoidance, emotional well-being, and hyperarousal in Iranian caregivers of women with advanced breast cancer. [PDF]

Discov Ment Health
Firoozi M, Sharifi M, Lewis CA, Arabi A, Esmati UA, Tadayyoni M, Lester D, Aboubakr HS.   +7 more
europepmc   +1 more source

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang, Ao Peng, Shuaiqiang Li, Yaning Huang, Jian Yan, Leyuan Wang, Zhihui Zhu, Fei‐Long Liu, Erbao Bian, Yang Liu, Dasheng Tian, Fenghe Li, Qi Liu   +12 more
wiley   +1 more source

A multicenter retrospective study of neoadjuvant chemotherapy and breast conservation rate in locally advanced breast cancer. [PDF]

Discov Oncol
Abu El-Ela RY, Hassan M, Kholosy RM, Kassem L.   +3 more
europepmc   +1 more source