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Advances in Radiotherapy for Breast Cancer

Surgical Oncology Clinics of North America, 2023
Breast cancer is the most prevalent cancer in women, and the second leading cause of cancer death in women in the United States. Radiation therapy is an important component in the multimodal management of breast cancer, including early stage and locally advanced breast cancers, as well as metastatic cases.
Rituraj, Upadhyay, Jose G, Bazan
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The Treatment of Advanced Breast Cancer

The American Journal of Nursing, 1962
of reigning supreme. In women throughout the United States, the breast is the most frequent single organ site of malignancy. Breast cancer is the leading cause of death of women in the prime of life, between 40 and 60 years of age. The incidence of this disease is incredibly high and shows no sign of declining.
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PROGESTAGENS AND ADVANCED BREAST CANCER

The Lancet, 1971
Abstract An interim analysis of the clinical responses in a controlled trial of œstrogens, an androgen, or a progestagen in the treatment of advanced breast cancer suggests that the progestagen used (17α-hydroxyprogesterone caproate 250 mg. intramuscularly three times a week) has no place in the management of generalised disease.
V, Jones   +7 more
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Olaparib for Advanced Breast Cancer

Future Oncology, 2020
Olaparib, an oral PARP-inhibitor, has shown clinical benefit for HER2-negative advanced breast cancer patients carrying a germinal BRCA1/2 mutation. In a randomized Phase III trial, olaparib significantly prolonged progression-free survival as compared with chemotherapy of physician choice.
Gaia, Griguolo   +4 more
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Management of Advanced Breast Cancer

Hormone Research, 2008
The systemic treatment of advanced breast cancer is not curative in intent but steady progress is being made which should lessen the morbidity from metastatic disease. Reference has been made to relevant posters presented at the International Symposium on Endocrine Therapy.
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Locally advanced breast cancer

Current Treatment Options in Oncology, 2000
Over the past 20 years, the prognosis for women diagnosed with locally advanced breast cancer (LABC; clinical stages IIB through IIIB) has improved significantly with recognition of the efficacy of multimodal therapy for reducing both local and distant recurrences, even in patients with inflammatory breast cancer (IBC).
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The control of advanced breast cancer

The American Journal of Surgery, 1963
Abstract The control of breast cancer is now a three stage process. The initial surgical attack, irradiation therapy and chemotherapy. All must be employed. The consideration of various hormonal therapies and chemotherapies requires a thorough knowledge of the effectiveness of each individual therapy.
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Trilostane in advanced breast cancer

Expert Opinion on Pharmacotherapy, 2006
Antiestrogens, principally tamoxifen, and aromatase inhibitors have been used as the first- and second-line therapy in patients with advanced postmenopausal breast cancer for many years. However, some patients acquire resistance to these treatments and, at present, further endocrine treatment is achieved by merely substituting the current medication ...
John R, Puddefoot   +2 more
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Hypophysectomy in advanced breast cancer

The American Journal of Surgery, 1965
THERE is undisputed evidence that the administration of steroid hormones or deprivation of hormone-producing tissues favorably modifies the anticipated behavior of advanced breast cancer. Extensive reviews have demonstrated the improvement that may be attained in selected patients after castration or adrenalectomy and the administration of estrogenic ...
B J, KENNEDY, L, FRENCH
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Gemcitabine in advanced breast cancer

Anti-Cancer Drugs, 1995
The experience with single-agent gemcitabine in advanced or metastatic breast cancer is reviewed. In all studies, gemcitabine was administered as a 30 min intravenous infusion in cycles once a week for 3 weeks followed by 1 week of rest. In the first European study (gemcitabine 800 mg/m2/week), of 40 evaluable patients, 14 were chemo-naive, 7 had ...
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