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Estradiol levels in women with hormone receptor-positive advanced breast cancer on fulvestrant therapy. [PDF]
Dai S +19 more
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Advances in the Treatment of Breast Cancer
Clinical Pharmacology & Therapeutics, 2007Breast cancer is the most commonly diagnosed cancer in American women and is the second leading cause of cancer-related deaths in this population. This review highlights how the use of a multidisciplinary approach to the management of diseases of the breast and the introduction of novel systemic therapies have improved the quality of life and survival ...
S, Moulder, G N, Hortobagyi
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Zoladex in Advanced Breast Cancer
Hormone Research, 2008In the treatment of 53 premenopausal patients with advanced breast cancer, the LHRH analogue, Zoladex (goserelin), produced a response rate similar to that of surgical oophorectomy. Endocrinologically, Zoladex caused castrate levels of serum oestradiol and progesterone except in a small number of patients, where intermittent, suppressed peaks of ...
J F, Robertson +3 more
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LOCALLY ADVANCED BREAST CANCER
Hematology/Oncology Clinics of North America, 1999The multidisciplinary management of patients with locally advanced breast cancer (LABC) has evolved over the last three decades. The introduction of chemotherapy (CT) and endocrine therapy in conjunction with surgery and radiation therapy (XRT) have changed the natural history of this disease.
F J, Esteva, G N, Hortobagyi
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Locally advanced breast cancer
Current Opinion in Obstetrics and Gynecology, 2006The management of locally advanced breast cancer requires a combined-modality treatment approach involving surgery, radiotherapy and systemic therapy. In this paper, we review clinical and experimental studies in order to evaluate how basic and clinical research in locally advanced breast cancer has progressed in the past year.
Sandro, Barni, Mario, MandalĂ
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Locally advanced breast cancer
Oncology Reports, 1996In vitro studies suggest p53 and bcl-2 may be important in the apoptotic response to irradiation, and that rapidly proliferating cells are more sensitive to radiotherapy. The clinical relevance of biological factors in predicting radiotherapy response was investigated in 62 patients with locally advanced breast cancer.
P, Willsher +5 more
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