Results 71 to 80 of about 410,880 (314)

Polymorphisms of the receptor for advanced glycation end products and glyoxalase I and long-term outcome in patients with breast cancer

Tumor Biology, 2017
Receptor for advanced glycation end products and glyoxalase I metabolizing advanced glycation end product precursors may play important role in the pathogenesis and progression of cancer.
Petra Tesarova, Tomas Zima, Ales A Kubena, Marta Kalousova   +3 more
doaj   +1 more source

Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer

Frontiers in Oncology, 2019
Dependence on the glutamine pathway is increased in advanced breast cancer cell models and tumors regardless of hormone receptor status or function. While 70% of breast cancers are estrogen receptor positive (ER+) and depend on estrogen signaling for ...
Diane M. Demas, Susan Demo, Yassi Fallah, Robert Clarke, Kenneth P. Nephew, Sandra Althouse, George Sandusky, Wei He, Ayesha N. Shajahan-Haq   +8 more
doaj   +1 more source

A pilot study of the use of human amniotic membrane as subcutaneous implants in a mouse model: a potential for temporary substitutes in two-stage breast reconstructions

BMC Women's Health, 2023
Introduction Breast reconstruction by prosthesis is frequently performed in breast cancer treatments, and a temporary substitute is used in the first step of two-stage operations.
Sadaf Alipour, Ramesh Omranipour, Bita Eslami, Solmaz Khalighfard, Azin Saberi, Azar Shabestari, Ali Mohammad Alizadeh   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Guidelines for diagnosis and treatment of advanced breast cancer in China (2022 edition)

Journal of the National Cancer Center
Breast cancer is the most common cancer among women worldwide. It has been estimated that about 416 000 new cases and over 117 000 deaths of breast cancer occurred in China in 2020.
doaj   +1 more source

Burden of early, advanced and metastatic breast cancer in The Netherlands

BMC Cancer, 2018
Background The aim of this study was to estimate the total economic and health related burden of breast cancer in the Netherlands. Methods Data on incidence, prevalence, mortality and survival were extracted from the Dutch National Cancer Registry and ...
G. T. Vondeling, G. L. Menezes, E. P. Dvortsin, F. G. A. Jansman, I. R. Konings, M. J. Postma, M. H. Rozenbaum   +6 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England. [PDF]

, 2009
Studies from the US have shown variations in breast cancer incidence, stage distribution, treatment and survival between ethnic groups. Data on 35 631 women diagnosed with breast cancer in South East England between 1998 and 2003 with self-assigned ...
Davies, E. A.; id_orcid, Jack, RH, Moller, H.; id_orcid, Møller, H, Davies, EA, Jack, Ruth H., H Møller, E A Davies, R H Jack   +8 more
core   +1 more source

Inflammatory Breast Cancer from Metastatic Ovarian Cancer

Case Reports in Obstetrics and Gynecology, 2016
Metastases to the breast from tumors other than breast carcinomas are extremely rare and represent only 0.2–1.3% of all diagnosed malignant breast tumors. Furthermore, while the most common sites for advanced ovarian cancer metastases are the liver, lung,
Vuthinun Achariyapota, Tuenjai Chuangsuwanich, Mongkol Benjapibal   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source