Results 71 to 80 of about 5,496,645 (302)
Burden of early, advanced and metastatic breast cancer in The Netherlands
BMC Cancer, 2018 Background The aim of this study was to estimate the total economic and health related burden of breast cancer in the Netherlands. Methods Data on incidence, prevalence, mortality and survival were extracted from the Dutch National Cancer Registry and ...G. T. Vondeling, G. L. Menezes, E. P. Dvortsin, F. G. A. Jansman, I. R. Konings, M. J. Postma, M. H. Rozenbaum +6 moredoaj +1 more sourceMissense variants in ATM in 26,101 breast cancer cases and 29,842 controls. [PDF]
, 2010 BACKGROUND: Truncating mutations in ATM have been shown to increase the risk of breast cancer but the effect of missense variants remains contentious.Schürmann, Peter, Olson, J.E., Seynaeve, C., Pita, Guillermo, Malcolm W.R. Reed, Beesley, Jonathan, Severi, G., Couch, Fergus J, Wang Gohrke, Shan, Jianjun Liu, Anton-Culver, H., Broeks, Annegien, Aittomaki, K., Kang, Daehee, Wang-Gohrke, Shan, Zachary Fredericksen, Hall, Katrine Blædel Pinholt, Kosma, V.M., Beckmann, Matthias W., Meindl, A., Heli Nevanlinna, Silva, Andreá Lema Da, Dunning, A.M., Morrison, J, Schmidt, Marjanka K., Keun-Young Yoo, van Leeuwen, F.E., Jenny Chang-Claude, Chang Claude, Jenny, Per Hall, Michael Bremer, Giles, Graham G., Georgia Chenevix-Trench, Fletcher, O, Noh, D.Y., Waltes, R., Silva, I. dos Santos, Brinton, L.A., Broeks, A., Bogdanova, Natalia V., Hopper, JL, Ekici, Arif B., Ashworth, Alan, Wang-Gohrke, S., Czene, Kamila, Smith, L (Letitia), Johnson, N., Orr, Nick, Spurdle, Amanda B., Van't Veer, L.J., Brinton, Louise A., Louise A. Brinton, Schurmann, P, Spurdle, AB, Flyger, Henrik, Melissa C. Southey, Kataja, V, Nordestgaard, Børge G., Douglas F. Easton, Veli-Matti Kosma, Kristiina Aittomäki, Liu, Jianjun, Elliott, Graeme, Ahmed, S., Zalutsky, Iosif V., Morrison, Jonathan, Pharoah, P.D., Bojesen, S.E., Breast Cancer Association Consortium, Lindblom, A., Platte, R., Platte, Radka, Spurdle, Amanda B, Kang, D., Pita, G., Johnson, N, Garcia-Closas, M., Olson, Janet E, Ko, Yon-Dschun, Nordestgaard, B.G., Antonenkova, N.N., Isabel dos Santos Silva, Fredericksen, Z, Milne, R.L., Laura Baglietto, Hopper, J.L., Cox, A, Manjeet K. Humphreys, García Closas, Montserrat, Nichola Johnson, Wang-Gohrke, S, Bojesen, Stig E., Dork, T., Milne, Roger L, Pharoah, P.D.P., Brauch, H, Brinton, LA, Reed, M.W.R., Humphreys, Manjeet K, Pita, G, Cox, Angela, Liu, J.J., Brock, I, AOCS Grp, Anton-Culver, H, Elliott, George Arthur, Olivia Fletcher, Ekici, Arif B, Marjanka K. Schmidt, Claus R. Bartram, Ian Brock, Jonathan Beesley, Bremer Michael, Peto, Julian, Johnson, Nichola, Dallas R. English, Giles, GG, Easton, Douglas F, Ashworth, A., Børge G. Nordestgaard, Alison M. Dunning, Radka Platte, Chenevix-Trench, G, Hall, Per, Lindblom, Annika, Annika Lindblom, Schurmann, P., Asperen, C.J. van, Ko, YD, GENICA Consortium, Baglietto, L, Humphreys, Manjeet K., Peter Devilee, Baglietto, Laura, Morrison, Ann Judith, Couch, FJ, Fasching, PA, Brinton, Louise A, English, Dallas R., Meindl, A, Severi, G, Brauch, H., Reed, Malcolm W. R., Nevanlinna, Heli, Burwinkel, B., Dong Young Noh, Jonathan Morrison, Reed, M.W., Bojesen, SE, John L. Hopper, Devilee, Peter, Orr, N, Javier Benítez, Hoda Anton-Culver, Lissowska, J, Tollenaar, Rob A E M, Bartram, CR, Giles, Graham G, Noh, DY, Schmidt, Marjanka K, Southey, Melissa C., Fredericksen, Z., Milne, RL, Beckmann, MW, Beesley, J, Yoo, Keun-Young, Blomqvist, Carl, Chanock, S., Milne, Roger L., Easton, Douglas F., Tuomas Heikkinen, Couch, Fergus J., Alan Ashworth, Schmidt, M.K., Benítez, Javier, Montserrat García-Closas, Wang, X.S., Giles, G.G., Fasching, Peter A., Barbara Burwinkel, Benitez, J, Schmutzler, RK, Dörk, Thilo, Peto, J., Couch, F.J., Angela Cox, Dunning, Alison M., Arif B. Ekici, Olson, Janet E., Kamila Czene, dos Santos Silva, Isabel, Mannermaa, A., Pharoah, Paul D. P., Stig E. Bojesen, Larsen, Marie Sofie Yoo, AOCS Group, Hiltrud Brauch, Blomqvist, C, Hamann, U., Chang-Claude, J., Tollenaar, Rob A. E. M., Vesa Kataja, Baglietto, L., Chenevix Trench, Georgia, Ahmed, Shahana, Veer, L.J. van 't, Wang, X., Strick, Reiner, Aittomaki, K, Strick, R, Bremer, M, Spurdle, A.B., Natalia V. Bogdanova, Margolin, Sara, Brock, I., Anton Culver, Hoda, Hopper, John L., Benitez, J., Hall, P, Waltes, Regina, Hamann, U, Zalutsky, Iosif V, Flora E. van Leeuwen, Anton-Culver, Hoda, Bogdanova, N.V., Antonenkova, NN, van Asperen, Christie J., Arias, J.I., Liu, J., Natalia N. Antonenkova, Henrik Flyger, Wang, XS, Wang, Xianshu, Liu, JJ, van Leeuwen, Flora E., Keith Humphreys, Yon-Dschun Ko, Morrison, J., Gaubert, Giles, Tollenaar, R.A., Janet E. Olson, Silva, Isabel dos Santos, Kataja, Vesa, Beckmann, Matthias W, Fasching, P.A., van Asperen, CJ, Ekici, A.B., Breast Canc Assoc Consortium, Ziogas, A, van Asperen, Christie J, Ziogas, Argyrios, Rita K. Schmutzler, Lissowska, J., Dunning, Alison M, Heikkinen, T., van 't Veer, L.J., Dunning, AM, Burwinkel, B, Czene, K, Broeks, A, Easton, DF, Tollenaar, Rob AEM, Tollenaar, RAEM, Kang, D, Zalutsky, IV, Hamann, Ute, Kosma, Veli-Matti, Dork,Thilo, Orr, N., English, D.R., Van't Veer, Laura J., Bogdanova, Natalia V, Chenevix-Trench, Georgia, Jolanta Lissowska, Humphreys, MK, Pharoah, Paul DP, Southey, M.C., Chang-Claude, J, Heikkinen, T, Sara Margolin, Ute Hamann, Rob A.E.M. Tollenaar, Smith, Letitia, Olson, JE, Annegien Broeks, Reed, MWR, Caroline Seynaeve, Leeuwen, F.E. van, Bremer, M., Roger L. Milne, Thilo Dörk, van Leeuwen, Flora E, Carl Blomqvist, Hall, P., Reed, Malcolm W R, Laura J. Van't Veer, Humphreys, K., Ziogas, A., Bojesen, Stig E, Schmutzler, R.K., Melanie Maranian, Ekici, AB, Iosif V. Zalutsky, Peto, J, Brauch, Hiltrud, Reed, Malcolm WR, Elliott, G., Amanda B. Spurdle, Chanock, Stephen, Julian Peto, Yoo, KY, Ignacio Arias, José, Bartram, Claus R., Smith, L., Beesley, J., Christie J. van Asperen, Beckmann, M.W., Daehee Kang, Argyrios Ziogas, van Leeuwen, FE, Strick, R., Yoo, K.Y., Arias, JI, Graeme Elliott, Devilee, P, Arias, José Ignacio, José Ignacio Arias, Ashworth, A, Hopper, John L, Nordestgaard, BG, Stephen Chanock, Lindblom, A, Meindl, Alfons, Bogdanova, NV, Hansen, Anne Lindblom, Arto Mannermaa, Humphreys, K, Margolin, S., Heikkinen, Tuomas, Ko, Yon Dschun, García-Closas, Montserrat, Fletcher, O., Flyger, H., Travis, Brandon Reed, Southey, MC, Aittomäki, Kristiina, Zalutsky, I.V., Reiner Strick, Elliott, G, Waltes, R, Nevanlinna, H., Fergus J. Couch, Schmutzler, Rita K., Orr, Nick; id_orcid, Nick Orr, English, Dallas R, van 't Veer, LJ (Laura), Guillermo Pita, Severi, Gianluca, English, DR, Yoo, Keun Young, Kosma, VM, Garcia-Closas, M, Pharoah, Paul D P, Seynaeve, Caroline, Shan Wang-Gohrke, Van't Veer, Laura J, Graham G. Giles, dos Santos Silva, I., Devilee, P., Nordestgaard, Børge G, Antonenkova, Natalia N., Peter A. Fasching, Czene, K., Paul D.P. Pharoah, Bremer, Michael, Platte, R, Maranian, Melanie, Silva, ID, Chanock, S, Maranian, M., Fletcher, Olivia, Shahana Ahmed, Burwinkel, Barbara, Humphreys, M.K., Southey, Melissa C, Pharoah, PDP, Antonenkova, Natalia N, Flyger, H, Margolin, S, Matthias W. Beckmann, Alfons Meindl, Mannermaa, A, Schmutzler, Rita K, Noh, Dong Young, Tollenaar, R.A.E.M., Dork, T, Cox, A., Nevanlinna, H, Bartram, Claus R, van Asperen, C.J., Kosma, Veli Matti, Ahmed, S (Shahana), Mannermaa, Arto, Easton, D.F., Chang-Claude, Jenny, Lissowska, Jolanta, Peter Schürmann, Ko, Y.D., Xianshu Wang, Brock, Ian, Silva, I.D., Chenevix-Trench, G., Kataja, V., Maranian, M, Humphreys, Keith, Fasching, Peter A, Regina Waltes, Fredericksen, Zachary, Gianluca Severi, Blomqvist, C., Letitia Smith, Bartram, C.R., kConFab Investigators, Silva, IDS, Fletcher, O;Johnson, N;Dos Santos Silva, I;Orr, N;Ashworth, A;Nevanlinna, H;Heikkinen, T;Aittomäki, K;Blomqvist, C;Burwinkel, B;Bartram, CR;Meindl, A;Schmutzler, RK;Cox, A;Brock, I;Elliott, G;Reed, MW;Southey, MC;Smith, L;Spurdle, AB;Hopper, JL;Couch, FJ;Olson, JE;Wang, X;Fredericksen, Z;Schürmann, P;Waltes, R;Bremer, M;Dörk, T;Devilee, P;van Asperen, CJ;Tollenaar, RA;Seynaeve, C;Hall, P;Czene, K;Humphreys, K;Liu, J;Ahmed, S;Dunning, AM;Maranian, M;Pharoah, PD;Chenevix-Trench, G;Beesley, J;Bogdanova, NV;Antonenkova, NN;Zalutsky, IV;Anton-Culver, H;Ziogas, A;Brauch, H;Ko, YD;Hamann, U;Fasching, PA;Strick, R;Ekici, AB;Beckmann, MW;Giles, GG;Severi, G;Baglietto, L;English, DR;Milne, RL;Benitez, J;Arias, JI;Pita, G;Nordestgaard, BG;Bojesen, SE;Flyger, H;Kang, D;Yoo, KY;Noh, DY;Mannermaa, A;Kataja, V;Kosma, VM;Garcia-Closas, M;Chanock, S;Lissowska, J;Brinton, LA;Chang-Claude, J;Wang-Gohrke, S;Broeks, A;Schmidt, MK;van Leeuwen, FE;Van't Veer, LJ;Margolin, S;Lindblom, A;Humphreys, MK;Morrison, J;Platte, R;Easton, DF +425 morecore +1 more sourceInhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli +10 morewiley +1 more sourceAusencia de la mutación BRCA1 del (exones 9-12) en familias con cáncer de seno / ovario fuera de hispanos mexicanos [PDF]
, 2009 3 páginasThe frequency and spectrum of germ line mutations in the
high-penetrance breast cancer susceptibility genes BRCA1
and BRCA2 shows considerable variation by ethnic group.Seidel Renkert, Antje, Colombian Breast Cancer Study Group (COLBCS), Torres, Diana, Seidel-Renkert, Antje, Rashid, Muhammad U., Briceño Balcázar, Ignacio, Weitzel, Jeffrey N., Hamann, Ute, Briceno, Ignacio +8 morecore +1 more sourceCirculating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong +6 morewiley +1 more source
