Results 51 to 60 of about 1,089,379 (264)
Frontiers in OncologyBackgroundHuman papillomavirus type 16 (HPV-16)-associated penile squamous cell carcinoma (PSCC) poses considerable therapeutic challenges, especially in its advanced stages.
Zhen-Kun Pan +3 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Cancer Management and Research, 2020 Chen Chen,1,2,* Xuanye Zhang,2,3,* Yixin Zhou,2,4,* Sha Fu,5 Zuan Lin,2,6 Shaodong Hong,2,3 Li Zhang2,3 1Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, People’s Republic of China; 2State Key Laboratory
Chen C +6 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Prognostic awareness and prognostic information preferences among advanced cancer patients in Kenya
African Journal of Primary Health Care & Family MedicineBackground: Cancer is the third leading cause of death in Kenya. Yet, little is known about prognostic awareness and preferences for prognostic information.
Hussein Elias +4 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
中西医结合护理Objective To explore the mechanism of resourcefulness in self-management efficacy and cancer-related fatigue in patients with advanced cancer, so as to provide reference for improving the fatigue level.
YIN Min (殷敏) +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A Perfect Blend of ‘Palliative Heart’ and ‘Oncology Brain’ in an Advanced Cancer Patient
NMO JournalCancer of the oesophagus is the 9th-most common cancer worldwide and the 5th-most common malignancy in India amongst both genders. It usually presents in an advanced stage, and approximately half of them have metastatic disease at the time of ...
Mrinalini Verma +2 more
doaj +1 more source