Results 31 to 40 of about 1,089,379 (264)

Quality of Life and Role of Palliative and Supportive Care for Patients With Brain Metastases and Caregivers: A Review

Frontiers in Neurology, 2022
Brain metastases (BM) are the most commonly diagnosed secondary brain lesions in adults, influencing these patients' symptoms and treatment courses. With improvements in oncologic treatments, patients with BM are now living longer with their advanced ...
Adela Wu, Gabriela Ruiz Colón, Michael Lim   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Effects of exercise intervention on sleep and survival in advanced cancer survivors: a meta-analysis of randomized controlled trials [PDF]

World Cancer Research Journal
Objective: The effectiveness of exercise in addressing sleep disturbance and improving survival outcomes among advanced cancer survivors remains inconsistent.
S. Liao, Y. Liu, W. Tang, Z. Zhang, M. Ha   +4 more
doaj   +1 more source

Own experience of surgical treatment for advanced cancer of the tongue and the mouth floor

Южно-Российский онкологический журнал, 2022
Purpose of the study. Improvement of surgical treatment outcomes in patients with advanced cancer of the tongue and the mouth floor providing radical surgery with preservation of the organ functions.Materials and methods.
P. V. Svetitskiy, I. V. Pustovaya, M. A. Engibaryan, M. V. Bauzhadze, A. K. Donskaya   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Multiple immune-related adverse events secondary to checkpoint inhibitor therapy in patients with advanced cancer: association with treatment effectiveness

Frontiers in Oncology
IntroductionCheckpoint inhibitors (CPI) are widely used in cancer treatment with a potential of causing immune-related adverse events (IRAEs). Several studies have reported a positive correlation between development of IRAEs and improved survival outcome.
Cecilia Olsson Ladjevardi, Cecilia Olsson Ladjevardi, Anthoula Koliadi, Anthoula Koliadi, Viktoria Rydén, Viktoria Rydén, Ali Inan El-Naggar, Evangelos Digkas, Evangelos Digkas, Antonios Valachis, Gustav J. Ullenhag, Gustav J. Ullenhag   +11 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Advanced prostate cancer [PDF]

Prostate Cancer and Prostatic Diseases, 1999
Both the definition and therapy of advanced prostate cancer is challenging. The advanced prostate cancer session at "The 8th International Prostate Cancer Update" had discussions which tried to answer the questions of management of these patients who either present with advanced disease or fail any form of therapy for clinically confined prostate ...
A M, Ziada, E D, Crawford
openaire   +2 more sources

Knowledge and use of prognostic scales by oncologists and palliative care physicians in adult patients with advanced cancer: A national survey (ONCOPRONO study)

Cancer Medicine, 2022
Background Prognostic scales exist to estimate patient survival in advanced cancer. However, there are no studies evaluating their use and practice.
Raphaëlle Dantigny, Fiona Ecarnot, Guillaume Economos, Elise Perceau‐Chambard, Stéphane Sanchez, Cécile Barbaret   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source