Results 21 to 30 of about 5,253,073 (166)

Risk of advanced colorectal neoplasia according to age and gender. [PDF]

, 2011
Colorectal cancer (CRC) is one of the leading causes of cancer related morbidity and death. Despite the fact that the mean age at diagnosis of CRC is lower in men, screening by colonoscopy or fecal occult blood test (FOBT) is initiated at same age in ...
Alexander Crispin, Burkhard Göke, Wagner, A., Crispin, Alexander, Göke, Burkhard, Frank T. Kolligs, Frank T Kolligs, Kolligs, Frank T., Andreas Wagner, Kolligs, F. T., Mansmann, Ulrich, Ulrich Mansmann, Wagner, Andreas, Axel Munte, Munte, A., Munte, Axel, Göke Burkhard, Wagner Andreas, Munte Axel, Crispin Alexander, Kolligs Frank T., Mansmann Ulrich   +21 more
core   +2 more sources

Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer.

, 2022
The retinoblastoma tumor suppressor (RB) is a critical regulator of E2F-dependent transcription, controlling a multitude of protumorigenic networks including but not limited to cell-cycle control.
Mandigo, AC, Schiewer, MJ, Yuan, W, Semenova, G, Vasilevskaya, IA, Knudsen, KE, Bogdan, D, de Bono, JS, Shafi, AA, Laufer, TS, Gallagher, L, McCann, JJ, Dylgjeri, E, McNair, CM   +13 more
core   +1 more source

Predictive factors for overall quality of life in patients with advanced cancer

, 2014
This study examined which domains/symptoms from the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 15 Palliative (QLQ-C15-PAL), an abbreviated version of the health-related EORTC QLQ-C30 ...
Cramarossa, Gemma;Chow, Edward;Zhang, Liying;Bedard, Gillian;Zeng, Liang;Sahgal, Arjun;Vassiliou, Vassilios;Satoh, Takefumi;Foro, Palmira;Ma, Brigette B. Y.;Chie, Wei-Chu;Chen, Emily;Lam, Henry;Bottomley, Andrew, 季瑋珠   +1 more
core   +1 more source

Supporting people with active and advanced disease: a rapid review of the evidence [PDF]

, 2014
1.1 Background: the NCSI AAD group The National Cancer Survivorship Initiative (NCSI, 2010) was set up in response to the NHS Cancer Reform Strategy (Department of Health, 2007) as a collaboration between Macmillan Cancer Support, the Department of ...
King, Nigel, Brooks, Joanna, Topping, Annie, Featherstone, Valerie A.   +3 more
core   +2 more sources

Advances in Gynecological Cancers

International Journal of Molecular Sciences, 2022
The burden of gynecological cancer constitutes a major focus of public health efforts, as it continues to represent a significant cause of cancer mortality, exerting not only physical and emotional distress but also serious financial strain upon individuals, caregivers, and communities [...]
Michalis Liontos, Oraianthi Fiste, Flora Zagouri, Meletios-Athanasios Dimopoulos   +3 more
openaire   +3 more sources

Anti-angiogenic therapy in patients with advanced gastric and gastroesophageal junction cancer: A systematic review

, 2017
[[abstract]]Despite advancements in therapy for advanced gastric and gastroesophageal junction cancers, their prognosis remains dismal. Tumor angiogenesis plays a key role in cancer growth and metastasis, and recent studies indicate that pharmacologic ...
Chen, LT;Oh, DY;Ryu, MH;Yeh, KH;Yeo, W;Carlesi, R;Cheng, R;Kim, J;Orlando, M;Kang, YK
core   +1 more source

RB/E2F1 as a Master Regulator of Cancer Cell Metabolism in Advanced Disease.

, 2021
Loss of the retinoblastoma (RB) tumor suppressor protein is a critical step in reprogramming biological networks that drive cancer progression, although mechanistic insight has been largely limited to the impact of RB loss on cell-cycle regulation. Here,
Vasilevskaya, IA, Domingo-Domenech, J, McNair, C, Thangavel, C, de Bono, JS, Paschalis, A, Laufer, TS, Xu, K, Mandigo, AC, Schiewer, MJ, Yuan, W, Sheehan, B, Guan, YF, Chand, SN, Knudsen, KE, Holst, J, Bogdan, D, Gallagher, P, Shafi, AA, Den, RB, McCue, PA, Pang, A, Gordon, N, McCann, JJ, Dylgjeri, E, Alec Paschalis, Karen E. Knudsen, Peter Gallagher, Jennifer J. McCann, Denisa Bogdan, Amy C. Mandigo, Robert B. Den, Jeff Holst, Talya S. Laufer, Beshara Sheehan, Matthew J. Schiewer, Saswati N. Chand, Christopher McNair, Ayesha A. Shafi, Josep Domingo-Domenech, Yi Fang Guan, Angel Pang, Wei Yuan, Nicolas Gordon, Irina A. Vasilevskaya, Johann S. de Bono, Chellappagounder Thangavel, Peter A. McCue, Kexin Xu, Emanuela Dylgjeri   +49 more
core   +1 more source

Advances in prostate cancer [PDF]

Current Opinion in Oncology, 1999
The causes of prostate cancer reflect a complex interaction between environmental and genetic factors. Improvement in screening has reduced the incidence of prostate cancer, and risk assessment schemata have enhanced therapy, both for localized disease and for locally recurrent prostate cancer.
Charles J, Ryan, Eric J, Small
openaire   +4 more sources

Usefulness of Comprehensive Genomic Profiling in Clinical Decision-Making in Oncology: A Systematic Review [PDF]

Journal of Immunotherapy and Precision Oncology
Biologic factors limiting responsiveness to matched targeted therapies include genomic heterogeneity and complexity. Advanced tumors with unique molecular profiles can be studied by comprehensive genomic profiling (CGP) and enhance patient outcomes using
Sewanti Limaye, Jayesh Deshmukh, Nitesh Rohatagi, Kumar Prabhash, Amit Rauthan, Shambhavi Singh, Arun Kumar   +6 more
doaj   +1 more source

Radical removal of advanced cancer of the oral cavity and oropharynx

Южно-Российский онкологический журнал, 2021
Surgery for advanced cancer of the oral cavity and oropharynx are among the most difficult. This is due to the topographical and anatomical features that limit the operating field and the proximity of the internal carotid artery, which penetrates into ...
P. V. Svetitskiy
doaj   +1 more source