Results 11 to 20 of about 5,253,073 (166)

Comparative Efficacy and Safety of Nivolumab and Nivolumab Plus Ipilimumab in Advanced Cancer: A Systematic Review and Meta-Analysis

Frontiers in Pharmacology, 2020
BackgroundCombination therapy with immune checkpoint inhibitors (ICIs) has been applied in the clinic to achieve synergistic effects and to improve clinical efficacy.
Yi Yang, Yi Yang, Gang Jin, Yao Pang, Yijie Huang, Wenhao Wang, Hongyi Zhang, Guangxin Tuo, Guangxin Tuo, Peng Wu, Peng Wu, Zequan Wang, Zijiang Zhu   +12 more
doaj   +1 more source

Perceived Dignity of Advanced Cancer Patients and Its Relationship to Sociodemographic, Clinical, and Psychological Factors

Frontiers in Psychology, 2022
ObjectiveLoss of dignity is one of the main reasons for wishing for an early death in patients with incurable diseases such as cancer and is strongly associated with psychological distress and loss of quality of life.
Berta Obispo, Patricia Cruz-Castellanos, Raquel Hernandez, Mireia Gil-Raga, Manuel González-Moya, Jacobo Rogado, Helena López-Ceballos, Miguel García-Carrasco, Paula Jiménez-Fonseca, Caterina Calderon   +9 more
doaj   +1 more source

Palliative Gastrointestinal Surgery in Patients With Advanced Peritoneal Carcinomatosis: Clinical Experience and Development of a Predictive Model for Surgical Outcomes

Frontiers in Oncology, 2022
BackgroundPalliative gastrointestinal (GI) surgery potentially relieves distressing symptoms arising from intestinal obstruction (IO) in patients with advanced peritoneal carcinomatosis (PC).
Jolene Si Min Wong, Jolene Si Min Wong, Jolene Si Min Wong, Jolene Si Min Wong, Sze Min Lek, Daniel Yan Zheng Lim, Claramae Shulyn Chia, Claramae Shulyn Chia, Claramae Shulyn Chia, Claramae Shulyn Chia, Grace Hwei Ching Tan, Grace Hwei Ching Tan, Chin-Ann Johnny Ong, Chin-Ann Johnny Ong, Chin-Ann Johnny Ong, Chin-Ann Johnny Ong, Chin-Ann Johnny Ong, Chin-Ann Johnny Ong, Melissa Ching Ching Teo, Melissa Ching Ching Teo, Melissa Ching Ching Teo, Melissa Ching Ching Teo   +21 more
doaj   +1 more source

Diagnostic models for impending death in terminally ill cancer patients: A multicenter cohort study

Cancer Medicine, 2021
Background Accurately predicting impending death is essential for clinicians to clarify goals of care. We aimed to develop diagnostic models to predict death ≤3 days in cancer patients.
Masanori Mori, Takuhiro Yamaguchi, Isseki Maeda, Yutaka Hatano, Takashi Yamaguchi, Kengo Imai, Ayako Kikuchi, Yosuke Matsuda, Kozue Suzuki, Satoru Tsuneto, David Hui, Tatsuya Morita, EASED collaborators   +12 more
doaj   +1 more source

Advancements in Cancer Immunotherapies

Vaccines, 2022
Recent work has suggested involvement of the immune system in biological therapies specifically targeting tumor microenvironment. Substantial advancement in the treatment of malignant tumors utilizing immune cells, most importantly T cells that play a key role in cell-mediated immunity, have led to success in clinical trials.
Ruchi Roy, Sunil Singh, Sweta Misra
openaire   +3 more sources

“3‐Day Surprise Question” to predict prognosis of advanced cancer patients with impending death: Multicenter prospective observational study

Cancer Medicine, 2021
Background The study aimed to clarify the efficacy of the “3‐Day Surprise Question (3DSQ)” in predicting the prognosis for advanced cancer patients with impending death.
Tomoo Ikari, Yusuke Hiratsuka, Takuhiro Yamaguchi, Isseki Maeda, Masanori Mori, Yu Uneno, Tomohiko Taniyama, Yosuke Matsuda, Kiyofumi Oya, Keita Tagami, Akira Inoue   +10 more
doaj   +1 more source

Advanced head and neck cancer: Long-term results of chemo-radiotherapy, complications and induction of second malignancies [PDF]

, 2001
Background: Chemo-radiotherapy is superior to radiotherapy alone in the treatment of advanced, inoperable head and neck cancer. The long-term treatment results, the induction of second malignant tumors, and other long-term toxicities are not well defined.
Schorer, H., Pohlmann, H., Munker, Reinhold, Aydemir, Ü., Reitmeier, M., Purmale, L., Hartenstein, R.   +6 more
core   +1 more source

CDK4/6 Inhibitors: Promising Opportunities beyond Breast Cancer. [PDF]

, 2016
Patnaik and colleagues report on the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of abemaciclib for the treatment of advanced solid cancers, demonstrating antitumor activity in advanced breast cancers as well as glioblastoma ...
Turner, NC, Yap, TA, Lim, JSJ
core   +1 more source

Exploratory Study Comparing End-of-Life Care Intensity between Chinese American and White Advanced Cancer Patients at an American Tertiary Medical Center

Palliative Medicine Reports, 2021
Background: Understanding ethnic disparities in end-of-life care (EOLC) intensity is central to improving outcomes for diverse populations. Although Chinese Americans represent one of the fastest growing ethnic groups in the United States, little is ...
Emma Ernst, Courtney Schroeder, Avery Caz Glover, Tamara Vesel   +3 more
doaj   +1 more source

Advanced prostate cancer [PDF]

Prostate Cancer and Prostatic Diseases, 1999
Both the definition and therapy of advanced prostate cancer is challenging. The advanced prostate cancer session at "The 8th International Prostate Cancer Update" had discussions which tried to answer the questions of management of these patients who either present with advanced disease or fail any form of therapy for clinically confined prostate ...
A M, Ziada, E D, Crawford
openaire   +2 more sources