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Treatment of Advanced Heart Failure

Cardiology in Review, 2000
The incidence of chronic heart failure has increased, with a corresponding increase in morbidity and mortality, and has made a substantial financial impact on our society. Improved therapy for heart failure has resulted in a significant prolongation of survival, a decreased number of hospitalizations, and an enhanced quality of life for many patients ...
M, Jessup, S, Brozena
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Advances in heart failure management

Medicina Clínica (English Edition)
Heart failure is a pathological condition characterized by substantial prevalence and mortality, particularly in the Western world. Over recent decades, both pharmacological and non-pharmacological interventions have emerged, significantly enhancing patient survival and overall quality of life.
José Luis, Zamorano   +1 more
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Management of advanced heart failure: a review

Expert Review of Cardiovascular Therapy, 2018
Heart failure (HF) has become a global pandemic. Despite recent developments in both medical and device treatments, HF incidences continues to increase. The current definition of HF restricts itself to stages at which clinical symptoms are apparent.
Kalmonovich, Eran   +11 more
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Frailty in Advanced Heart Failure

Heart Failure Clinics, 2016
Frailty is defined as a biological syndrome reflecting impaired physiologic reserve and heightened vulnerability to stressors. The evolving profile of heart failure (HF), increased survival of aging patients with complex comorbidities in parallel with the growing population undergoing mechanical circulatory support as lifetime therapy, means that ...
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Advanced Therapies for Advanced Heart Failure in Women

Heart Failure Clinics, 2019
Women with advanced heart failure (HF) are underrepresented in trials of short-term and durable mechanical circulatory support although they derive similar benefit. In acute HF, intensive medical and interventional therapies are effective but underutilized.
Marlena V, Habal   +2 more
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Heart Failure: Advanced Refractory Heart Failure.

FP essentials, 2021
End-stage heart failure (HF) is associated with an extremely poor prognosis. Progressive and/or persistent HF signs and symptoms in the setting of optimal therapy is the hallmark of more advanced disease. Physicians must be able to recognize patients with features of refractory HF to aid in timely evaluation for advanced therapy options.
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Recent advances in the diagnosis of heart failure

Current Cardiology Reports, 2004
Heart failure has reached epidemic proportions and the prevalence is increasing. The accurate and efficient diagnosis of heart failure remains problematic, as signs and symptoms are neither sensitive nor specific. Recent advances in the diagnosis of this condition include a conceptual change in what constitutes heart failure, a greater understanding of
James O, O'Neill, David O, Taylor
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Surgical Treatments for Advanced Heart Failure

Surgical Clinics of North America, 2009
Patients with heart failure represent a significantly ill cohort, and the survival of the most advanced heart failure patients is dismal with medical management alone. This cohort of advanced heart-failure patients benefits from several surgical treatments.
Mani A, Daneshmand, Carmelo A, Milano
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Management of Advanced or Refractory Heart Failure

Revista Española de Cardiología (English Edition), 2004
Advanced heart failure, also be defined as stage D heart failure, characterized by advanced structural heart disease and marked symptoms of heart failure at rest despite dietary modification, salt restriction and maximal medical therapy including ACE inhibitors, angiotensin II receptor blockers, digitalics, diuretics and beta blockers.
María G, Crespo Leiro   +1 more
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Heart failure: advances through genomics

Nature Reviews Genetics, 2011
Heart failure is an increasingly prevalent and highly lethal disease that is most often caused by underlying pathologies, such as myocardial infarction or hypertension, but it can also be the result of a single gene mutation. Comprehensive genetic and genomic approaches are starting to disentangle the diverse molecular underpinnings of both forms of ...
Esther E, Creemers   +2 more
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