Results 1 to 10 of about 5,897 (148)
Use of intravenous lipid emulsions in drug-induced toxicities: a 2025 narrative review [PDF]
Annals of Intensive CareIntravenous lipid emulsions (ILE) were first proposed in 1998 as a treatment for bupivacaine-induced cardiac arrest. Since then, their use has expanded to include poisonings by various lipophilic drugs such as tricyclic antidepressants, calcium channel ...
Gauthier Nendumba +4 more
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Effects of statins on serum sCD40, sCD146 and PAPP-An in patients with coronary heart disease [PDF]
Journal of Medical BiochemistryBackground: To analyse the effects of statins on the levels of sCD40, sCD146 and PAPP-An in patients with coronary heart disease (CHD). Methods: 126 patients with CHD treated from September 2022 to September 2024 were divided into a study group (n = 84 ...
Li Huawen +3 more
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3-Cyano-2-oxa-pyridines: a promising template for diverse pharmacological activities [PDF]
Journal of Advanced Biomedical and Pharmaceutical Sciences, 2021 Pyridines have occupied a unique place in medicinal chemistry as it is widely profound as natural products and formed the integral backbone of great number of drugs in the market.
Gamal El-Din Abuo-Rahma +5 more
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Acute poisoning by cardiovascular agents [PDF]
Vojnosanitetski Pregled, 2003 In order to determine the frequency, severity of poisoning, and the efficacy of the applied therapeutic measures, retrospective study of 391 patients treated for acute drug poisoning was performed during one-year period at the Clinic for Emergency and ...
Vučinić Slavica +5 more
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Steroids—has the time come to extend their use to AML?
Journal of the Egyptian National Cancer Institute, 2021 Background In 2018, leukaemia accounted for 2.6% of all new cancers, it being the 13th most common cause of cancer and the 10th most common cause of cancer death. Glucocorticoids are commonly used in lymphoid leukaemia treatment, where they are cytotoxic.
Mariah Farrugia +3 more
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Antiviral activity of ouabain against a Brazilian Zika virus strain
Scientific Reports, 2022 Zika virus (ZIKV) is an emerging arbovirus associated with neurological disorders. Currently, no specific vaccines or antivirals are available to treat the ZIKV infection.
Deyse Cristina Madruga Carvalho +9 more
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Cardiac Glycosides as Immune System Modulators
Biomolecules, 2021 Cardiac glycosides (CGs) are natural steroid compounds occurring both in plants and animals. They are known for long as cardiotonic agents commonly used for various cardiac diseases due to inhibition of Na+/K+-ATPase (NKA) pumping activity and modulating
Jan Škubník +2 more
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Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics
Biomolecules, 2021 Cardiac glycosides are natural sterols and constitute a group of secondary metabolites isolated from plants and animals. These cardiotonic agents are well recognized and accepted in the treatment of various cardiac diseases as they can increase the rate ...
Ranjith Kumavath +6 more
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Viruses, 2021 Therapeutic options for coronaviruses remain limited. To address this unmet medical need, we screened 5406 compounds, including United States Food and Drug Administration (FDA)-approved drugs and bioactives, for activity against a South Korean Middle ...
Meehyun Ko +12 more
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Frontiers in Pharmacology, 2023 Aberrant mitophagy has been identified as a driver for energy metabolism disorder in most cardiac pathological processes. However, finding effective targeted agents and uncovering their precise modulatory mechanisms remain unconquered.
Ji-Chao Zhou +20 more
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