Results 1 to 10 of about 1,506,940 (201)
Aims Heart failure with reduced ejection fraction (HFrEF) is a disease with high mortality and morbidity. Recent positive inotropic drug developments focused on cardiac myofilaments, that is, direct activators of the myosin molecule and Ca2+ sensitizers ...
Arnold Péter Ráduly +9 more
doaj +1 more source
Background. Implementation of mechanical circulatory support and heart transplantation technologies in paediatric clinical practice is changing approaches of diagnostics and treatment of heart failure (HF) in children. The experience of carrying out such
Larisa A. Balykova +7 more
doaj +1 more source
Hemodynamic Profile of the Cardiotonic Agent Pimobendan
Pimobendan (UD-CG 115 BS) is a potent positive inotropic agent with vasodilatory properties. This hemodynamic profile was demonstrated in conscious rabbits chronically instrumented with Doppler flow probes. Pimobendan (10, 30, 100, and 300 micrograms/kg i.v.) increased cardiac output, stroke volume, heart rate, and mesenteric, renal, and hindquarter ...
J C, van Meel, W, Diederen
openaire +3 more sources
An Evaluation of Traditional Persian Medicine for the Management of SARS-CoV-2
A new coronavirus causing severe acute respiratory syndrome (SARS-CoV-2) has emerged and with it, a global investigation of new antiviral treatments and supportive care for organ failure due to this life-threatening viral infection.
Roodabeh Bahramsoltani +3 more
doaj +1 more source
Digitalis glycosides,a group of cardiotonic agents for heart failure,have been used for a long time,but may often trigger arrhythmias as a result of digitalis intoxication.It is of great significance in finding a method to reduce their toxicity and ...
MA Shu-hua1 +8 more
doaj +2 more sources
FUNDAMENTO: A levosimendana é um novo agente inotrópico que aumenta a contratilidade cardíaca sem aumentar a captação celular de cálcio, de forma a não causar sobrecarga de cálcio e arritmias relacionadas.
Osman Can Yontar +4 more
doaj
Pandanus odoratissimus Linn. (family: Pandanaceae) is traditionally recommended by the Indian Ayurvedic medicines for treatment of headache, rheumatism, spasm, cold/flu, epilepsy, wounds, boils, scabies, leucoderma, ulcers, colic, hepatitis, smallpox ...
Prafulla P. Adkar, V. H. Bhaskar
doaj +1 more source
A series of novel 4,5-dihydro-5-methyl-6-(2 or 4-substituted 7-quinazolinyl)-3(2H)-pyridazinones was synthesized and examined for cardiotonic activity in anesthetized dogs. The 4-substituted aminoquinazolines generally showed potent and long-lasting inotropic activity.
NOMOTO, Yuji +3 more
openaire +3 more sources
Identification of Bioactive Agents and Immunomodulatory Factors from Seashells of the Persian Gulf
Background: Research in marine pharmacology will promise new bioactive agents. The marine bioenvironment is the unique resource for bioactive agents that could not be found in terrestrial organisms.
Arezoo Najafi +3 more
doaj
Objective: to substantiate a procedure for predicting the severity of postperfusion acute heart failure (AHF) from the baseline level of NT-proBNP during myocardial revascularization in patients with a left ventricular ejection fraction (LVEF) of less ...
V. V. Moroz +6 more
doaj +1 more source

