Procedural Characteristics and Safety of Slender Percutaneous Coronary Intervention: Slender Is Better. [PDF]
ABSTRACT Objectives We aimed to examine the procedural characteristics and safety profile of slender percutaneous coronary interventions (PCI) using a 5 Fr or smaller sheath. Background Smaller catheter size has been associated with fewer complications in PCI.
Yoshimachi F +11 more
europepmc +2 more sources
Clinical Characteristics and Treatment of Atrial Fibrillation and Heart Failure: a Multicenter Survey [PDF]
Background Atrial fibrillation (AF) is a common clinical tachyarrhythmia with high prevalence, and a predisposing factor of stroke. In addition, it has a causal relationship with heart failure (HF) .
HU Huachao, CHEN Xianya, XIE Siyuan, XIA Zhen, XIAO Hua
doaj +1 more source
Lipid Emulsion to Treat Acute Poisonings: Mechanisms of Action, Indications, and Controversies
Biodetoxification using intravenous lipid emulsion (ILE) in acute poisoning is of growing interest. As well as for local anesthetics, ILE is currently used to reverse toxicity caused by a broad-spectrum of lipophilic drugs.
Karim Jaffal +2 more
doaj +1 more source
Therapeutic Effect of Echium amoenum on Isoproterenol-Induced Heart Failure in Male Rat [PDF]
Background and objectives: Echium amoenum has shown anti-inflammatory and antioxidants properties and is suggested for heart disease in Persian medicine. Methods: To evaluate its cardioprotective effects, 50 male Wistar rats were divided into five groups:
Hossein Jafari +6 more
doaj +1 more source
Precision medicine considerations for the management of heart disease and stroke in East Asians
Heart disease is the leading cause of death in Asian Americans. Importantly, people of East Asian descent are more likely to carry a loss-of-function point mutation in aldehyde dehydrogenase 2 (ALDH2), ALDH2*2, which reduces ALDH2 enzymatic activity by ...
Candida L Goodnough, Eric R Gross
doaj +1 more source
OBJECTIVES: Memantine is an N-methyl-d-aspartate (NMDA) glutamate receptor antagonist used to treat Alzheimer's disease. Previous studies have suggested that receptor blockers act as neuroprotective agents; however, no study has specifically investigated
Adriano Meneghini +6 more
doaj +1 more source
Propyl Gallate, a Strong Antioxidant, Increases the Ca2+ Sensitivity of Cardiac Myofilament
Ca2+ sensitizers are cardiotonic agents that directly increase the Ca2+ sensitivity of cardiac myofilament. To find a novel Ca2+ sensitizer, we have screened a group of phenolic compounds by examining their effects on the Ca2+-dependent force generation ...
Naoto Tadano +5 more
doaj +1 more source
Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria [PDF]
Objective(s): Recently, we showed that some new synthetic compounds structurally related to cilostamide (4-(1,2-dihydro-2-oxoquinolin-6-hydroxy)- N-cyclohexyl-N-methylbutanamide), a selective phosphodiesterase 3 (PDE3) inhibitor, produce inotropic effect
Azar Hosseini +3 more
doaj +1 more source
Melanoma is the most common cancer in young adults, with a constantly increasing incidence. Metastatic melanoma is a very aggressive cancer with a 5-year survival rate of about 22−25%.
Laura Soumoy +8 more
doaj +1 more source
D RUGS THAT INCREASE the positive inotropic (ie, cardiotonic) potential of the myocardium are used in a variety of clinical settings. All catecholamines exert their inotropic effects by stimulating adrenergic mediated receptors in the sympathetic nervous system.
Roberta Hines, Stephen Harris
openaire +1 more source

