Results 11 to 20 of about 5,916 (165)

Procedural Characteristics and Safety of Slender Percutaneous Coronary Intervention: Slender Is Better. [PDF]

open access: yesCatheter Cardiovasc Interv
ABSTRACT Objectives We aimed to examine the procedural characteristics and safety profile of slender percutaneous coronary interventions (PCI) using a 5 Fr or smaller sheath. Background Smaller catheter size has been associated with fewer complications in PCI.
Yoshimachi F   +11 more
europepmc   +2 more sources

Clinical Characteristics and Treatment of Atrial Fibrillation and Heart Failure: a Multicenter Survey [PDF]

open access: yesZhongguo quanke yixue, 2023
Background Atrial fibrillation (AF) is a common clinical tachyarrhythmia with high prevalence, and a predisposing factor of stroke. In addition, it has a causal relationship with heart failure (HF) .
HU Huachao, CHEN Xianya, XIE Siyuan, XIA Zhen, XIAO Hua
doaj   +1 more source

Lipid Emulsion to Treat Acute Poisonings: Mechanisms of Action, Indications, and Controversies

open access: yesPharmaceutics, 2023
Biodetoxification using intravenous lipid emulsion (ILE) in acute poisoning is of growing interest. As well as for local anesthetics, ILE is currently used to reverse toxicity caused by a broad-spectrum of lipophilic drugs.
Karim Jaffal   +2 more
doaj   +1 more source

Therapeutic Effect of Echium amoenum on Isoproterenol-Induced Heart Failure in Male Rat [PDF]

open access: yesResearch Journal of Pharmacognosy
Background and objectives: Echium amoenum has shown anti-inflammatory and antioxidants properties and is suggested for heart disease in Persian medicine. Methods: To evaluate its cardioprotective effects, 50 male Wistar rats were divided into five groups:
Hossein Jafari   +6 more
doaj   +1 more source

Precision medicine considerations for the management of heart disease and stroke in East Asians

open access: yesCardiology Plus, 2020
Heart disease is the leading cause of death in Asian Americans. Importantly, people of East Asian descent are more likely to carry a loss-of-function point mutation in aldehyde dehydrogenase 2 (ALDH2), ALDH2*2, which reduces ALDH2 enzymatic activity by ...
Candida L Goodnough, Eric R Gross
doaj   +1 more source

Memantine prevents cardiomyocytes nuclear size reduction in the left ventricle of rats exposed to cold stress

open access: yesClinics, 2009
OBJECTIVES: Memantine is an N-methyl-d-aspartate (NMDA) glutamate receptor antagonist used to treat Alzheimer's disease. Previous studies have suggested that receptor blockers act as neuroprotective agents; however, no study has specifically investigated
Adriano Meneghini   +6 more
doaj   +1 more source

Propyl Gallate, a Strong Antioxidant, Increases the Ca2+ Sensitivity of Cardiac Myofilament

open access: yesJournal of Pharmacological Sciences, 2009
Ca2+ sensitizers are cardiotonic agents that directly increase the Ca2+ sensitivity of cardiac myofilament. To find a novel Ca2+ sensitizer, we have screened a group of phenolic compounds by examining their effects on the Ca2+-dependent force generation ...
Naoto Tadano   +5 more
doaj   +1 more source

Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
Objective(s): Recently, we showed that some new synthetic compounds structurally related to cilostamide (4-(1,2-dihydro-2-oxoquinolin-6-hydroxy)- N-cyclohexyl-N-methylbutanamide), a selective phosphodiesterase 3 (PDE3) inhibitor, produce inotropic effect
Azar Hosseini   +3 more
doaj   +1 more source

Toad Venom Antiproliferative Activities on Metastatic Melanoma: Bio-Guided Fractionation and Screening of the Compounds of Two Different Venoms

open access: yesBiology, 2020
Melanoma is the most common cancer in young adults, with a constantly increasing incidence. Metastatic melanoma is a very aggressive cancer with a 5-year survival rate of about 22−25%.
Laura Soumoy   +8 more
doaj   +1 more source

New cardiotonic agents

open access: yesSeminars in Anesthesia, Perioperative Medicine and Pain, 1996
D RUGS THAT INCREASE the positive inotropic (ie, cardiotonic) potential of the myocardium are used in a variety of clinical settings. All catecholamines exert their inotropic effects by stimulating adrenergic mediated receptors in the sympathetic nervous system.
Roberta Hines, Stephen Harris
openaire   +1 more source

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