Results 41 to 50 of about 8,494 (210)

Bufalin Inhibits Cytokine Storm by Regulating TLR4/TLR3 Signaling Pathway

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Bufalin is one main component of the dried venom from Bufo gargarizans Cantor, which has anti‐tumor, cardiotonic, anti‐inflammatory and other physiological activities. However, in recent years, researchers have mainly paid attention to its anti‐tumor effect and neglected its anti‐inflammatory effect.
Xixi Liu   +11 more
wiley   +1 more source

シンキキョウシンヤクSCH00013ノモルモットシンゾウニタイスルサヨウ [PDF]

open access: yes, 2016
 A new cardiotonic agent, SCH00013 (SCH), which was synthesized by Zenyaku Kogyo Company, Limited, exhibits cardiotonic effects by enhancing calcium sensitivity [1].
堀田 芳弘   +2 more
core   +1 more source

Studies on cardiotonic agents. VII. Potent cardiotonic agent KF15232 with myofibrillar Ca2+ sensitizing effect.

open access: yesChemical and Pharmaceutical Bulletin, 1991
A series of novel 4,5-dihydro-5-methyl-6-(2 or 4-substituted 7-quinazolinyl)-3(2H)-pyridazinones was synthesized and examined for cardiotonic activity in anesthetized dogs. The 4-substituted aminoquinazolines generally showed potent and long-lasting inotropic activity.
Y, Nomoto, H, Takai, T, Ohno, K, Kubo
openaire   +3 more sources

Pandanus odoratissimus (Kewda): A Review on Ethnopharmacology, Phytochemistry, and Nutritional Aspects

open access: yesAdvances in Pharmacological Sciences, 2014
Pandanus odoratissimus Linn. (family: Pandanaceae) is traditionally recommended by the Indian Ayurvedic medicines for treatment of headache, rheumatism, spasm, cold/flu, epilepsy, wounds, boils, scabies, leucoderma, ulcers, colic, hepatitis, smallpox ...
Prafulla P. Adkar, V. H. Bhaskar
doaj   +1 more source

Exploring the Cancer Therapeutic Potential of Traditional Medicinal Plants by Modulating the Apoptotic Pathway

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Cancer is a versatile disease with a high rate of relapse and mortality. Despite the presence of various treatment modalities, there is a serious need for the development of its management. Phytochemicals, which are abundant in nature, can be turned into novel medications for these types of diseases by optimizing their functions and ...
Mithila Kulkarni   +5 more
wiley   +1 more source

Nicotiana tabacum: From a Beneficial Plant to Harmful Products—A Comprehensive Review of Smokeless Tobacco and Its Adverse Health Effects

open access: yesThe Scientific World Journal, Volume 2026, Issue 1, 2026.
Nicotiana tabacum is a cash crop that originated in America and was introduced to the world by Christopher Colombus. It is now cultivated in many countries with major producers including China, the USA, India, and Brazil. The plant was widely used by the indigenous people of America for different reasons (spiritual, hallucination, and medical).
Abir Chami   +4 more
wiley   +1 more source

Identification of Bioactive Agents and Immunomodulatory Factors from Seashells of the Persian Gulf

open access: yesIranian South Medical Journal, 2010
Background: Research in marine pharmacology will promise new bioactive agents. The marine bioenvironment is the unique resource for bioactive agents that could not be found in terrestrial organisms.
Arezoo Najafi   +3 more
doaj  

Origins of Plant Derived Medicines [PDF]

open access: yes, 2008
This review article describes the origins of plant derived medicines that have been developed as a result of traditional knowledge being handed down from one generation to the next.
De Britto, A. John, Maridass, Muthia
core   +1 more source

Efficacy of pimobendan in the prevention of congestive heart failure or sudden death in doberman pinschers with preclinical dilated cardiomyopathy (the PROTECT study) [PDF]

open access: yes, 2012
<p>Background: The benefit of pimobendan in delaying the progression of preclinical dilated cardiomyopathy (DCM) in Dobermans is not reported.</p> <p>Hypothesis: That chronic oral administration of pimobendan to Dobermans with ...
Boswood, A.   +15 more
core   +3 more sources

Deuteration of Six‐Membered N‐Heteroarenes: Chemistry and Applications

open access: yesChemistry – A European Journal, Volume 31, Issue 67, December 1, 2025.
Deuterated six‐membered N‐Heteroarenes (6NHetAr) are finding utility in an increasing repertoire of applications. Our paper comprehensively reviews synthetic approaches that have been reported for the deuteration of 6NHetAr and their fused counterparts while providing an overview of established and emerging applications for these materials.
Liju Raju   +4 more
wiley   +1 more source

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