Results 61 to 70 of about 8,494 (210)

Biomolecular Interaction Prediction: The Era of AI

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This review offers a thorough examination of recent progress in deep learning for predicting biomolecular interactions, including those involving proteins, nucleic acids, and small molecules. It covers data processing strategies, representative model architectures, and evaluation metrics, while highlighting current methodological limitations.
Haoping Wang, Xiangjie Meng, Yang Zhang
wiley   +1 more source

Efficacy of different cardiotonic drug on severity of endotoxemia under heart failure coupled with systemic inflammatory syndrome in experiments

Кубанский научный медицинский вестник, 2015
On the model of systemic inflammatory response syndrome caused by toxi-allergic myocarditis 10-day duration in rabbits the efficacy of 5 days (beginning after 5 days from the injection of staphylococcus toxins) administration of the various ...
D. I. Ionov, M. M. Fedorova, G. V. Sukoyan, P. A. Galenko-Yaroshevsky, N. V. Gongadze   +4 more
doaj  

NEWER CARDIOTONIC AGENTS – BENEFICIAL EFFECTS ON NEWBORN MYOCARDIUM [PDF]

Pediatric Research, 1987
Previous data has suggested a deleterious action of Amrinone (Am) on newborn (NB) myocardium. An investigation of the relationship between dose, age, and contractility has been undertaken using isolated right ventricular papillary muscles from NB (0-5 days), juvenile (J) (18-29 days), and adult (A) New Zealand white rabbits.
Thomas S Klitzner, Timothy L Degner, Ross R Ravin, William F Friedman   +3 more
openaire   +1 more source

The Nutritional and Bioactive Components, Potential Health Function and Comprehensive Utilization of Hawthorn: A Review

Food Frontiers, Volume 6, Issue 5, Page 2108-2128, September 2025.
This review systematically and comprehensively analyzes hawthorn (Crataegus spp.), covering its bioactive constituents, properties, and processed products. ABSTRACT Hawthorn is widely cultivated in China, with excellent varieties and steadily increasing production.
Wenteng Yang, Quanhong Gao, Kun Ran, Mingyue Jiao, Xiaodan Fu, Zhenlin Han, Chao Liu, Ningyang Li   +7 more
wiley   +1 more source

The association between red blood cell transfusion timing and the development of retinopathy of prematurity: Application of the two‐phase theory

Acta Ophthalmologica, Volume 103, Issue 6, Page 645-651, September 2025.
Abstract Purpose Red blood cell (RBC) transfusions are believed to be associated with retinopathy of prematurity (ROP), but the underlying mechanism is not fully understood, partly due to the lack of information on RBC transfusion timing. The aim was to determine the association between the timing and amount of RBC transfusions and the development and ...
Salma El Emrani, Lizanne A. Derks, Angela M. Tjiam, Michaela van Bohemen, Jacqueline U. M. Termote, Lotte E. van der Meeren, Irwin K. M. Reiss, H. Rob Taal, Enrico Lopriore, Nicoline E. Schalij‐Delfos   +9 more
wiley   +1 more source

Single crystal X-ray structure of 3-amino-5-(4-chlorophenyl)pyridazine-4-carbonitrile [PDF]

, 2013
The title compound 3-amino-5-(4-chlorophenyl)pyridazine-4-carbonitrile was prepared by a one-pot three-component reaction of malononitrile with corresponding arylglyoxal in the presence of hydrazine hydrate at room temperature in water and ethanol.
Ahmad Poursattar Marjani, Hooman Yaghoobnejad Asl, Jabbar Khalafy, Somaye Farajzadeh   +3 more
core   +1 more source

Trajectories of Physical Activity During a 6‐Month Mobile App‐Based Lifestyle Modification Intervention in Physically Inactive Adults With Cardiovascular Risk Factors

Scandinavian Journal of Medicine &Science in Sports, Volume 35, Issue 8, August 2025.
ABSTRACT Mobile app‐based health promotion allows frequent and longitudinal monitoring of lifestyle modifications for cardiovascular prevention. We explored the trajectories of physical activity (PA) during mobile app‐based disease management programs in adults with cardiovascular risk using group‐based trajectory modeling (GBTM). Male participants who
Takuji Adachi, Takahiro Miki, Kotoe Shimizu, Masashi Kanai, Yuta Hagiwara   +4 more
wiley   +1 more source

Bassia indica Attenuates Cardiotoxicity in a Rat Model via Anti-Inflammatory, Antioxidant, and Keap1/Nrf2 Modulation

Pharmaceuticals
Background: Drug-induced cardiotoxicity is a primary concern in clinical practice, especially in the context of oxidative stress induced by anti-cancer, antiviral, and antidiabetic drugs.
Fayyaz Anjum, Saad Touqeer, QurratUlAin Jamil, Ayesha Rida, Hafiz Muhammad Zubair, Adeel Sarfraz, Saleh Alfuraih, Waad Alrohily, Ali F. Almutairy, Ashfaq Ahmad, Mohammed Aufy, Shahid Muhammad Iqbal   +11 more
doaj   +1 more source

Antioxidant and antimicrobial properties of 2-(4,5-dihydro-1H-pyrazol-1-yl)-pyrimidine and 1-carboxamidino-1H-pyrazole derivatives [PDF]

, 2010
Five previously synthesized 4-trifluoromethyl-2-(5-aryl-3-styryl-1H-pyrazol-1yl)-pyrimidines and six 5-aryl-3-styryl-1-carboxamidino-1H-pyrazole derivatives were screened for their antioxidant proprieties.
COLEPICOLO, Pio, FLORES, Alex F. C., FLORES, Darlene C., GRESSLER, Vanessa, MOURA, Sidnei, PINTO, Ernani   +5 more
core   +1 more source

THE NEUROPROTECTIVE EFFECTS OF HAWTHORN-BASED MEDICATIONS

Паёми Сино
The purpose of this review is to summarize and organize the existing literature data on the antidepressant activity of drugs derived from plants in the genus Crataegus L.
Kurkin Vladimir Aleksandrovich, Kudashkina Nataliya Vladimirovna, Zaripov Nurali Abdurakibovich, Pravdivtseva Olga Evgenievna, Zaytseva Elena Nikolaevna, Khasanova Svetlana Rashitovna   +5 more
doaj   +1 more source