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Conceptualizing myocardial contractility as an emergent property that characterizes myocardial contraction [PDF]

open access: yesFrontiers in Physiology
Myocardial contractility (MC) is a fundamental concept that is widely used to describe the cardiac muscles’ mechanical function, yet its definitions in textbooks and literature are vague, inconsistent, and often contradictory.
Serena Y. Kuang, Gorune Geloian
doaj   +4 more sources

Acetate suppresses myocardial contraction via the short-chain fatty acid receptor GPR43 [PDF]

open access: yesFrontiers in Physiology, 2022
The heart has high energy requirements, with an estimated 40%–60% of myocardial ATP production derived from the oxidation of fatty acids under physiological conditions.
Xuan Jiang   +10 more
doaj   +2 more sources

Speckle tracking echocardiography analyses of myocardial contraction efficiency predict response for cardiac resynchronization therapy [PDF]

open access: yesCardiovascular Ultrasound, 2018
Background In patients with left ventricular (LV) dysssynchrony, contraction that doesn’t fall into ejection period (LVEj) results in a waste of energy due to inappropriate contraction timing, which was now widely treated by cardiac resynchronization ...
Zibire Fulati   +6 more
doaj   +2 more sources

Modulation of Myocardial Contraction by Peroxynitrite [PDF]

open access: yesFrontiers in Physiology, 2012
Peroxynitrite is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on ...
Mark eKohr   +3 more
doaj   +3 more sources

Myocardial Contraction during the Diastolic Isovolumetric Period: Analysis of Longitudinal Strain by Means of Speckle Tracking Echocardiography [PDF]

open access: yesJournal of Cardiovascular Development and Disease, 2018
Background: According to the ventricular myocardial band model, the diastolic isovolumetric period is a contraction phenomenon. Our objective was to employ speckle-tracking echocardiography (STE) to analyze myocardial deformation of the left ventricle ...
Vicente Mora   +10 more
doaj   +2 more sources

Regulation of myocardial contraction as revealed by intracellular Ca2+ measurements using aequorin [PDF]

open access: yesJournal of Physiological Sciences
Of the ions involved in myocardial function, Ca2+ is the most important. Ca2+ is crucial to the process that allows myocardium to repeatedly contract and relax in a well-organized fashion; it is the process called excitation–contraction coupling.
Satoshi Kurihara, Norio Fukuda
doaj   +2 more sources

Left ventricle ejection fraction and strain derived by three-dimensional echocardiography are associated with exercise capacity in the patients with heart failure [PDF]

open access: yesVojnosanitetski Pregled, 2019
Background/Aim. Echocardiography represents the most commonly performed noninvasive cardiac imaging tests for the patients with heart failure (HF). The aim of this study was to assess the relationship between the exercise capacity parameters [peak oxygen
Pavlović-Kleut Milena   +2 more
doaj   +1 more source

Association between aortic stenosis severity and contractile reserve measured by two-dimensional strain under low-dose dobutamine testing [PDF]

open access: yesVojnosanitetski Pregled, 2013
Background/Aim. Early detection of left ventricle (LV) systolic dysfunction could be a clue for surgical treatment in patients with significant aortic stenosis (AS).
Banović Marko   +5 more
doaj   +1 more source

The role of myocardial mechanical and QTc dispersion in detecting significant coronary artery disease

open access: yesJournal of Medicine in Scientific Research, 2022
Background Prolonged myocardial contraction and QT interval duration may be found in ischemic viable myocardium, yet it is unclear if noninvasive examination of regional nonhomogeneous myocardial mechanics and QT duration may detect patients with ...
Mohamed R Badran
doaj   +1 more source

SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice

open access: yesScientific Reports, 2021
Transverse-tubules (T-tubules) play pivotal roles in Ca2+-induced, Ca2+ release and excitation–contraction coupling in cardiomyocytes. The purpose of this study was to uncover mechanisms where sarco/endoplasmic reticulum Ca2+ ATPase (SERCA2a) improved ...
Shuai Wang   +9 more
doaj   +1 more source

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