Computational modeling of acute myocardial infarction [PDF]
, 2016 This is an Accepted Manuscript of an article published by Taylor & Francis Group in Computer Methods in Biomechanics and Biomedical Engineering on October, 2016, available online at: http://www.tandfonline.com/10.1080/10255842.2015.1105965Myocardial ...
Kuhl, E., Sáez Viñas, Pablo
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Dynamic finite-strain modelling of the human left ventricle in health and disease using an immersed boundary-finite element method [PDF]
, 2014 Detailed models of the biomechanics of the heart are important both for developing improved interventions for patients with heart disease and also for patient risk stratification and treatment planning.
Berry, Colin +4 more
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β-adrenergic inhibition prevents action potential and calcium handling changes during regional myocardial ischemia [PDF]
, 2017 β-adrenergic receptor (β-AR) blockers may be administered during acute myocardial infarction (MI), as they reduce energy demand through negative chronotropic and inotropic effects and prevent ischemia-induced arrhythmogenesis. However, the direct effects
Domondon, Philip +7 more
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A coupled mitral valve -- left ventricle model with fluid-structure interaction
, 2017 Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now possible to ...
Brown, André EX +11 more
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Eigenhearts for diagnosis of congestive heart failure (CHF) [PDF]
, 2006 Common cardiac diseases such as cardio-myopathy, coronary artery diseases, and valve diseases, result in abnormal myocardial movement, which could eventually lead to heart failure, also called congestive heart failure (CHF). CHF is a disease in which the
Ahanathapillai, Vijayalakshmi +1 more
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Bifurcations in valveless pumping techniques from a coupled fluid-structure-electrophysiology model in heart development [PDF]
, 2017 We explore an embryonic heart model that couples electrophysiology and muscle-force generation to flow induced using a $2D$ fluid-structure interaction framework based on the immersed boundary method.
Battista, Nicholas A., Miller, Laura A.
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Myocardial contraction-relaxation coupling
American Journal of Physiology-Heart and Circulatory Physiology, 2010 Since the pioneering work of Henry Pickering Bowditch in the late 1800s to early 1900s, cardiac muscle contraction has remained an intensely studied topic for several reasons. The heart is located centrally in our body, and its pumping motion demands the attention of the observer.
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STUDIES ON MYOCARDIAL CONTRACTION
The Keio Journal of Medicine, 1969 The relations between the right ventricular contraction and the local myo-cardial shortening measured by means of the transcatheter method were dis-cussed. The local tension-velocity-length relationships were also shown.The authors wish to express their sincere gratitude to Prof. H. Sasamoto for his generous guidance and instruction in this study.
HARUO TOMODA +6 more
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Estimating prognosis in patients with acute myocardial infarction using personalized computational heart models [PDF]
, 2017 Biomechanical computational models have potential prognostic utility in patients after an acute ST-segment–elevation myocardial infarction (STEMI). In a proof-of-concept study, we defined two groups (1) an acute STEMI group (n = 6, 83% male, age 54 ± 12 ...
Berry, Colin +5 more
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Short term doxycycline treatment induces sustained improvement in myocardial infarction border zone contractility. [PDF]
, 2018 Decreased contractility in the non-ischemic border zone surrounding a MI is in part due to degradation of cardiomyocyte sarcomeric components by intracellular matrix metalloproteinase-2 (MMP-2).
Aguayo, Esteban +11 more
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