Results 21 to 30 of about 83,934 (252)

Mechanisms of the “No-Reflow” Phenomenon After Acute Myocardial Infarction

JACC: Basic to Translational Science, 2023
Summary: Pericytes contract during myocardial ischemia resulting in capillary constriction and no reflow. Reversing pericyte contraction pharmacologically reduces no reflow and infarct size. These findings open up an entire new venue of research aimed at
Sanjiv Kaul, MD, Carmen Methner, PhD, Zhiping Cao, PhD, Anusha Mishra, PhD   +3 more
doaj   +1 more source

Lipofundin® MCT/LCT 20% increase left ventricular systolic pressure in an rat heart model via increase of intracellular calcium level [PDF]

Korean Journal of Anesthesiology, 2016
BackgroundLipid emulsions have been used to treat various drug toxicities and for total parenteral nutrition therapy. Their usefulness has also been confirmed in patients with local anesthetic-induced cardiac toxicity.
Jiyoung Park, Yeon A Kim, Jeong Yeol Han, Sangkyu Jin, Seong-Ho Ok, Ju-Tae Sohn, Heon-Keun Lee, Young-Kyun Chung, Il-Woo Shin   +8 more
doaj   +1 more source

Effect of αα₂-adrenoceptor stimulation on the isolated rat heart after acute myocardial infarction

КардиоСоматика
Background: α2-Adrenoceptors (α2-ARs) are a family of G protein–coupled receptors. They are located on presynaptic membranes of adrenergic fibers, postsynaptic membranes of cardiomyocytes and vascular smooth muscle cells, as well as in the peripheral and
Anna M. Kuptsova, Nafisa I. Ziyatdinova, Aiziriak M. Sadykov, Timur L. Zefirov   +3 more
doaj   +1 more source

Angina de Prinzmetal Angina de Prinzmetal Prinzmetal's angina

Arquivos Brasileiros de Cardiologia, 2009
Essa síndrome é causada por um espasmo focal de uma artéria coronária epicárdica, levando a isquemia miocárdica grave. Embora freqüentemente acredite-se que o espasmo ocorra em artérias sem estenose, muitos pacientes com angina de Prinzmetal apresentam ...
Eduardo Contreras Zuniga, Juan Esteban Gomez Mesa, Sandra Ximena Zuluaga Martinez, Vanesa Ocampo, Cristian Andres Urrea   +4 more
doaj   +1 more source

Direct effects of glucose administration on heart rate, myocardial contraction, and duration of cardiac cycle in frog's heart

Journal of the Practice of Cardiovascular Sciences, 2018
Background: Recent and emerging evidences show that glucose ingestion causes prolonged Q-T interval and can trigger arrhythmia. Objective: The objective of this study is to examine the effects of administration of glucose solutions on the heart rate ...
B I Waziri, A Shahzad
doaj   +1 more source

Myocardial contraction-relaxation coupling

American Journal of Physiology-Heart and Circulatory Physiology, 2010
Since the pioneering work of Henry Pickering Bowditch in the late 1800s to early 1900s, cardiac muscle contraction has remained an intensely studied topic for several reasons. The heart is located centrally in our body, and its pumping motion demands the attention of the observer.
openaire   +3 more sources

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Measurement of Cardiac Mechanical Function in Isolated Ventricular Myocytes from Rats and Mice by Computerized Video-Based Imaging

Biological Procedures Online, 2001
Isolated adult cardiac ventricular myocytes have been a useful model for cardiovascular research for more than 20 years. With the recent advances in cellular physiology and transgenic techniques, direct measurement of isolated ventricular myocyte ...
Ren Jun, Wold Loren
doaj   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Recent Developments in Cardiac Contractility Modulation for Heart Failure [PDF]

Texas Heart Institute Journal
None.
Joshua R. Hirsch, MD, Hamid Afshar, MD
doaj   +1 more source