Results 171 to 180 of about 4,843,849 (291)

Maternal outcomes according to fetal head station at diagnosis of the second stage of labor

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study determines the association between fetal head station (FHS) at the diagnosis of the second stage of labor and adverse maternal outcomes. Methods This retrospective cohort study was conducted at a single university‐affiliated tertiary medical center from 2011 to 2023, including singleton vertex deliveries at ≥ 37 weeks of ...
Itamar Gilboa   +6 more
wiley   +1 more source

Longitudinal blood pressure trajectories before 20 weeks of gestation and adverse outcomes in women with chronic hypertension

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To explore the different patterns in early‐pregnancy mean arterial pressure (MAP) trajectories before 20 weeks of gestation in pregnant women with chronic hypertension, and whether it can stratify risk for adverse perinatal outcomes.
Haoyu Zuo   +4 more
wiley   +1 more source

Recombinant activated factor VIIa for severe postpartum hemorrhage in Africa: Evidence, appropriate use, and research priorities—A narrative review

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Postpartum hemorrhage (PPH) accounts for 30%–50% of maternal mortality in Africa and occurs in the context of pre‐existing anemia, limited blood product availability, delayed recognition, and constrained referral systems. Although bundle‐based care (E‐MOTIVE), early tranexamic acid (TXA), and uterotonics have substantially improved outcomes, a
Johnny Mahlangu   +3 more
wiley   +1 more source

Emerging Human‐Based Research Technologies for Investigating the Pathomechanisms and Therapies for Vascular Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

open access: yesiNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang   +3 more
wiley   +1 more source

A Recovery-Focused Framework for the Management of Cardiogenic Shock. [PDF]

open access: yesCirc Heart Fail
Kyriakopoulos CP   +4 more
europepmc   +1 more source

Structural Covariance Analysis of Altered Brain Development in Neonates With Congenital Heart Disease After Surgery

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Brain development is altered in neonates with congenital heart disease (CHD), with well‐characterised reductions in regional brain volumes and enlargement of CSF spaces. However, perioperative morphological changes remain incompletely understood. Purpose To identify brain regions showing spatial patterns of coordinated expansion and
Mirthe E. M. van der Meijden   +14 more
wiley   +1 more source

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