Goal-directed therapy in cardiovascular surgery: A case series study [PDF]
Hemodynamic and intravascular volume monitoring has been utilized and significantly improved thanks to the technology revolution. Goal-Directed Therapy (GDT) derived from this advanced monitoring is beneficial for complex surgeries, and it shifted the ...
Nader Givtaj +5 more
doaj +2 more sources
The incidence of myocardial injury following post-operative Goal Directed Therapy [PDF]
Background Studies suggest that Goal Directed Therapy (GDT) results in improved outcome following major surgery. However, there is concern that pre-emptive use of inotropic therapy may lead to an increased incidence of myocardial ischaemia and infarction.
Fawcett Jayne +5 more
doaj +6 more sources
Goal-directed therapy: what is the goal again? [PDF]
Recent attention has focused on intraoperative hypotension (IOH) and hemodynamic instability. This enhanced awareness to limit IOH, combined with fluid restriction and increased vasopressor use, has been associated with an increase in postoperative acute
Amy Yerdon +5 more
doaj +2 more sources
Early and individualized goal-directed therapy for trauma-induced coagulopathy [PDF]
Severe trauma-related bleeding is associated with high mortality. Standard coagulation tests provide limited information on the underlying coagulation disorder.
Schöchl Herbert +4 more
doaj +3 more sources
OCOSO2: study protocol for a single-blinded, multicentre, randomised controlled trial assessing a central venous oxygen saturation-based goal-directed therapy to reduce postoperative complications in high-risk patients after elective major surgery [PDF]
Background Fluid loading-based goal-directed therapy is a cornerstone of anaesthesia management in major surgery. Its widespread application has contributed to a significant improvement in perioperative morbidity and mortality.
Bruno Pastene +9 more
doaj +2 more sources
Goal-Directed Therapy: New Trends and Horizons [PDF]
In traumatized or critically ill patients suffering from a variety of severe illnesses, survival often depends on the successful handling of a chain of time-critical events with the ultimate goal to provide sufficient tissue oxygenation. Timely initiated goal-directed therapy (GDT) is a cornerstone in the care and treatment of these patients.
Mikhail Kirov +3 more
doaj +3 more sources
Transcranial Doppler goal-directed therapy after cardiac arrest (GOODYEAR): a feasibility study [PDF]
Aim: Hypoxic Ischemic Brain Injury is a major cause of death after cardiac arrest. Identifying optimal mean arterial pressure (MAP) targets to restore brain oxygen delivery remains challenging.
Juliette Meunier +7 more
doaj +2 more sources
Preoperative goal directed therapy in geriatric hip fracture patients – a retrospective quality improvement study [PDF]
Background Hip fractures in older adults are common and carry a high risk of morbidity and mortality. Preoperative dehydration, a key risk factor for adverse outcomes, is often underdiagnosed at admission.
Nicole Vollenweider +5 more
doaj +2 more sources
Early goal-directed therapy: Sorting through confusion
Mitchell M Levy
doaj +3 more sources
Critical care ultrasound goal-directed versus early goal-directed therapy in septic shock. [PDF]
Yu K +5 more
europepmc +4 more sources

