Results 11 to 20 of about 492,815 (298)

Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis [PDF]

New England Journal of Medicine, 2017
BACKGROUND: After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials (ProCESS, ARISE, and ProMISe) showed no benefit.
Angus, DC, Bailey, M, Barnato, AE, Bellomo, R, Canter, RR, Coats, TJ, Delaney, A, Gimbel, E, Grieve, RD, Harrison, DA, Higgins, AM, Howe, B, Huang, DT, Kellum, JA, Mouncey, PR, Music, E, Peake, SL, Pike, F, Reade, MC, Rowan, KM, Sadique, MZ, Singer, M, Yealy, DM   +22 more
core   +3 more sources

Is Off-pump cardiac surgery ready for goal-directed therapy? [PDF]

Annals of Cardiac Anaesthesia, 2017
Cor Slagt
doaj   +2 more sources

Goal-Directed Fluid Therapy Based on Pulse-Pressure Variation Compared with Standard Fluid Therapy in Patients Undergoing Complex Spine Surgery: A Randomized Controlled Trial [PDF]

Asian Spine Journal, 2022
Study Design Prospective, randomized, controlled study. Purpose To determine whether the use of goal-directed fluid therapy (GDT) guided by pulse-pressure variation (PPV) and fluid management protocol can reduce intraoperative hypotension, blood ...
Karuna Wongtangman, Sirichai Wilartratsami, Nattachai Hemtanon, Supinya Tiviraj, Manee Raksakietisak   +4 more
doaj   +1 more source

Perioperative Goal-Directed Therapy [PDF]

Journal of Cardiothoracic and Vascular Anesthesia, 2014
From the Department of Anesthesiology, Duke University, Durham, North Carolina. T.E.M. is a consultant for Edwards Lifesciences, Covidien, and Hospira. Research funding from Cheetah Medical and Retia Medical. T.J.G. is a consultant for Baxter, Edwards Life Science, Hospira and QRx.
Waldron, Nathan H, Miller, Timothy E, Gan, Tong J   +2 more
openaire   +2 more sources

Perioperative Hemodynamic Optimization in Patients at Risk for Delirium – A Randomized-Controlled Trial

Frontiers in Medicine, 2022
BackgroundPost-operative delirium is common in elderly patients and associated with increased morbidity and mortality. We evaluated in this pilot study whether a perioperative goal-directed hemodynamic optimization algorithm improves cerebral oxygenation
Kristina E. Fuest, Ariane Servatius, Bernhard Ulm, Stefan J. Schaller, Stefan J. Schaller, Bettina Jungwirth, Bettina Jungwirth, Manfred Blobner, Manfred Blobner, Sebastian Schmid, Sebastian Schmid   +10 more
doaj   +1 more source

Correlation of GDFT combined with rehabilitation therapy in DNA damage repair of esophageal cancer cells

Frontiers in Genetics, 2023
Esophageal cancer is a common malignant tumor with a high incidence and a serious threat to human health. The treatment of esophageal cancer is a complex process, which requires the comprehensive use of a variety of treatment methods.
Lihua Yan, Yajun Ji
doaj   +1 more source

Goal-directed therapy in osteoporosis [PDF]

Journal of Bone and Mineral Research, 2013
Themanagement of osteoporosis is changing—for the better. Perhaps the most progressive recent step has been the assessment of fracture risk using clinical risk factors through tools such as the Fracture Risk Assessment Tool (FRAX). In addition to traditional intervention thresholds, such as those for osteoporosis defined by the WHO T-score or prior ...
Eugene, McCloskey, William D, Leslie
openaire   +2 more sources

Goal-directed haemodynamic therapy (GDHT) in surgical patients: systematic review and meta-analysis of the impact of GDHT on post-operative pulmonary complications

Perioperative Medicine, 2020
Background Perioperative goal-directed haemodynamic therapy (GDHT), defined as the administration of fluids with or without inotropes or vasoactive agents against explicit measured goals to augment blood flow, has been evaluated in many randomised ...
Ahilanandan Dushianthan, Martin Knight, Peter Russell, Michael PW Grocott   +3 more
doaj   +1 more source

Goal-directed therapy in intraoperative fluid and hemodynamic management. [PDF]

, 2013
Intraoperative fluid management is pivotal to the outcome and success of surgery, especially in high-risk procedures. Empirical formula and invasive static monitoring have been traditionally used to guide intraoperative fluid management and assess volume
Gutierrez, Maria Cristina, Liu, Hong, Moore, Peter G   +2 more
core   +1 more source

Hemodynamic optimization in severe trauma: a systematic review and meta-analysis. [PDF]

, 2014
OBJECTIVE: Severe trauma can be associated with significant hemorrhagic shock and impaired organ perfusion. We hypothesized that goal-directed therapy would confer morbidity and mortality benefits in major trauma.
Arulkumaran, N, Ball, J, Cecconi, M, Corredor, C, Grounds, MR, Hamilton, MA, Rhodes, A   +6 more
core   +3 more sources