Is early goal-directed therapy associated with a higher risk of adverse events? [PDF]
Journal of Intensive Care, 2018 The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 suggested against the use of the early goal-directed therapy (EGDT) in patients with septic shock.
Ahmad Sabry Saleh
doaj +3 more sources
Hepatic Perfusion Alterations in Septic Shock Patients: Impact of Early Goal-directed Therapy [PDF]
Chinese Medical Journal, 2016 Background: Early goal-directed therapy (EGDT) has become an important therapeutic management in early salvage stage of septic shock. However, splenic organs possibly remained hypoperfused and hypoxic despite fluid resuscitation.
Xi-Wen Zhang +7 more
doaj +3 more sources
Early goal-directed therapy: Sorting through confusion
Lung India, 2015 Mitchell M Levy
doaj +4 more sources
Feasibility and beneficial effects of an early goal directed therapy after cardiac arrest: evaluation by conductance method [PDF]
Scientific Reports, 2021 Although beneficial effects of an early goal directed therapy (EGDT) after cardiac arrest and successful return of spontaneous circulation (ROSC) have been described, clinical implementation in this period seems rather difficult.
Ole Broch +9 more
doaj +2 more sources
Efficacy of early goal-directed therapy for hemodynamics stability in off-pump coronary artery bypass surgery [PDF]
Scientific ReportsOff-pump coronary artery bypass surgery causes hemodynamic changes due to position and surgical manipulation, which directly affect cardiovascular function and increase the rate of postoperative complications.
Bui Quoc Khanh +7 more
doaj +2 more sources
Assessment of early goal-directed therapy guideline adherence: Balancing clinical importance and feasibility. [PDF]
PLoS ONE, 2019 BackgroundAssessing adherence to Early goal-directed therapy (EGDT) is challenging and might account for the negative findings and generalisability of the major trials to a real-life setting.
Thansinee Saetae +2 more
doaj +2 more sources
Early and individualized goal-directed therapy for trauma-induced coagulopathy [PDF]
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2012 Severe trauma-related bleeding is associated with high mortality. Standard coagulation tests provide limited information on the underlying coagulation disorder.
Schöchl Herbert +4 more
doaj +4 more sources
Echocardiogram-guided resuscitation versus early goal-directed therapy in the treatment of septic shock: a randomized, controlled, feasibility trial [PDF]
Journal of Intensive Care, 2018 Objective Echocardiography is often used to guide septic shock resuscitation, but without evidence for efficacy. We conducted an intensive care unit (ICU)-based randomized controlled feasibility trial comparing echocardiography-guided septic shock ...
Michael J. Lanspa +5 more
doaj +2 more sources
Early goal-directed therapy using a physiological holistic view: the ANDROMEDA-SHOCK—a randomized controlled trial [PDF]
Annals of Intensive Care, 2018 Background Septic shock is a highly lethal condition. Early recognition of tissue hypoperfusion and its reversion are key factors for limiting progression to multiple organ dysfunction and death.
Glenn Hernández +12 more
doaj +2 more sources