Success of applying early goal-directed therapy for septic shock patients in the emergency department. [PDF]
Panita Worapratya,1 Apisit Wanjaroenchaisuk,2 Jutharat Joraluck,3 Prasit Wuthisuthimethawee1 1Department of Emergency Medicine, Songklanagarind Hospital, Faculty of Medicine, Prince of Songkla University, Songkhla, 2Emergency Department, Samitivej ...
Worapratya P +3 more
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OBJECTIVES: Acute kidney injury is associated with many conditions, and no interventions to improve the outcomes of established acute kidney injury have been developed.
Cristina Prata Amendola +14 more
doaj +2 more sources
Sepsis in pregnancy and early goal-directed therapy. [PDF]
Sepsis is a major cause of serious morbidity and mortality in pregnant women and their babies. Conventional management has evolved over many years. Improved understanding of the underlying pathophysiology and randomized clinical trials have led to recommendations for the formalization and standardization of the management of severe sepsis in non ...
Joseph J, Sinha A, Paech M, Walters BN.
europepmc +4 more sources
Hemodynamic early goal-directed therapy: Explaining the fine print. [PDF]
The management of patients after cardiothoracic surgery can be very complex. Variabilities exist in hemodynamic status after cardiac surgery and the use of cardiopulmonary bypass - all of which can have a significant impact on myocardial Frank-Starling curves.
Goldthwaite Z, Firstenberg MS, Botsch A.
europepmc +4 more sources
Predictors of unattempted central venous catheterization in septic patients eligible for early goal-directed therapy. [PDF]
Introduction: Central venous catheterization (CVC) can be an important component of the management of patients with severe sepsis and septic shock. CVC, however, is a time- and resource-intensive procedure associated with serious complications.
Vinson DR +7 more
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Critical care ultrasound goal-directed versus early goal-directed therapy in septic shock. [PDF]
Yu K +5 more
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Factors associated with nonadherence to early goal-directed therapy in the ED. [PDF]
Protocol-driven early goal-directed therapy (EGDT) has been shown to reduce mortality in patients with severe sepsis and septic shock in the ED. EGDT appears to be underused, even in centers with formalized protocols. The aim of our study was to identify factors associated with not initiating EGDT in the ED.This was a cohort study of 340 EGDT-eligible ...
Mikkelsen ME +9 more
europepmc +4 more sources
Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE. [PDF]
Prior to 2001 there was no standard for early management of severe sepsis and septic shock in the emergency department. In the presence of standard or usual care, the prevailing mortality was over 40-50 %.
Nguyen HB +21 more
europepmc +8 more sources
Barriers of Implementing Early Goal-Directed Therapy Among Critically Ill Patients with Sepsis [PDF]
Although early goal-directed therapy (EGDT) has been found to improve mortality in critically ill patients with severe sepsis/septic shock, its implementation in the emergency department (ED) can be challenging. objectives.
Haitham Mohamed +3 more
doaj +1 more source
The effects of norepinephrine infusion combined with goal-directed fluid therapy on delayed graft function in patients undergoing kidney transplantations: study protocol for a multicenter randomized controlled trial. [PDF]
Background Chronic kidney disease presents a formidable challenge to global healthcare systems. With ongoing advancements in surgical techniques, kidney transplantation has emerged as a principal therapeutic modality for individuals afflicted with end ...
Shi M +5 more
europepmc +2 more sources

