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Early goal-directed treatment is an evidence-based approach to guide hemostatic therapy during major periprocedural bleeding. If viscoelastic coagulation tests are not available, an algorithm, termed the pyramid of hemostatic interventions, can help ...
Barna Babik +2 more
doaj +1 more source
Hyperlactatemia and hypotension: looking at septic shock from different perspectives
The last decade has witnessed significant improvements in the treatment of patients with severe sepsis and septic shock, and a reduction in mortality from septic syndromes has been described by several epidemiological studies.
Daniele Coen
doaj +1 more source
Crystalloids versus colloids for goal-directed fluid therapy in major surgery [PDF]
INTRODUCTION: Perioperative hypovolemia arises frequently and contributes to intestinal hypoperfusion and subsequent postoperative complications. Goal-directed fluid therapy might reduce these complications.
Hiltebrand, Luzius +19 more
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Management of Sepsis and Septic Shock: What Have We Learned in the Last Two Decades?
Sepsis is a clinical syndrome encompassing physiologic and biological abnormalities caused by a dysregulated host response to infection. Sepsis progression into septic shock is associated with a dramatic increase in mortality, hence the importance of ...
Shiwani Kamath +2 more
doaj +1 more source
Perioperative goal-directed therapy - What is the evidence? [PDF]
Perioperative goal-directed therapy aims at optimizing global hemodynamics during the perioperative period by titrating fluids, vasopressors, and/or inotropes to predefined hemodynamic goals.
Saugel, Bernd +2 more
core +1 more source
Time to antimicrobial therapy in septic shock patients treated with an early goal‐directed resuscitation protocol: A post‐hoc analysis of the ARISE trial [PDF]
OBJECTIVE: Intravenous antimicrobial therapy within 1 h of the diagnosis of septic shock is recommended in international sepsis guidelines. We aimed to evaluate the association between antimicrobial timing and mortality in patients presenting to the ED ...
Webb, SAR +65 more
core +2 more sources
Personalised anaesthesia, arterial blood gases and tissue hypoxia: modulating postoperative regeneration and healing [PDF]
The fundamental limiting factor of major surgery is the body's ability to regenerate and heal tissue after it has been operated on, but this process must take its own course.
Jayaram Jacynta +8 more
doaj +1 more source
Treatment Guidelines of Severe Sepsis and Septic Shock [PDF]
Severe sepsis and septic shock are common health care problem with high mortality. In 2001, Early goal directed therapy was introduced, early appropriate therapy impact on the outcome. In 2012, the “Surviving Sepsis Campaign: International Guidelines for
Soonyoung Park, Sang-Bum Hong
doaj +1 more source
Parent-Child Interaction Therapy
Parent-child interaction therapy is a parent-mediated therapy approach that focuses on solving internalization-externalization problems observed in children aged 2-7.
Sümeyye Ulaş +2 more
doaj +1 more source
Key components of early goal directed therapy.
Key components of early goal directed therapy.
Rujipat Samransamruajkit (6470519) +2 more
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