Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley +1 more source
Two-Stage Transvenous Implantable Cardioverter-Defibrillator Lead Extraction Guided by 3D Transesophageal Echocardiography in Severe Cardiomyopathy: A Case Report. [PDF]
Sikka T, Ahmad T, Musuku S.
europepmc +1 more source
Abstract Exertional heat illness (EHI) and exertional rhabdomyolysis (ER) are increasingly recognized causes of morbidity in competitive and tactical athletes. Cardiac troponin (cTn) elevation, traditionally viewed as a marker of myocardial necrosis, may also be seen in these settings and can create significant diagnostic and prognostic uncertainty ...
John‐Henry L. Dean +2 more
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Evolving Evidence-Driven Strategies in Cardiogenic Shock Management. [PDF]
Bhardwaj A +5 more
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This preclinical study evaluated a novel controlled‐expansion expanded polytetrafluoroethylene (ePTFE)‐covered transjugular intrahepatic portosystemic shunt (TIPS) stent in 11 swine, demonstrating 100% technical success, excellent deployability, and durable 6‐month angiographic patency without thrombosis, migration, fracture, or device‐related toxicity.
Yi Xiang +15 more
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New Insights into Cardiac Intensive Care. [PDF]
Chen C, Wu Y, Wang B.
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Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
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Autonomic nervous system dysfunction in critically ill cancer patients: Hemodynamic consequences and multimodal assessment strategies. [PDF]
Gong S, Chu Y, Wang X.
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Recompensation of Cirrhosis: A New Treatment‐Related Disease State
This perspective article conceptualizes recompensation of cirrhosis as a distinct treatment‐related disease state rather than mere transient clinical improvement after etiology‐directed therapy, and further proposes a four‐state classification including compensated cirrhosis, stable recompensation, unstable recompensation, and persistent decompensation
Wentao Tan +5 more
wiley +1 more source
Continuous Spinal Anesthesia in a High-Risk Patient With Pulmonary Hypertension Undergoing Hip Fracture Repair: A Case Report. [PDF]
El Kaissi J, Laoutid J.
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