Results 71 to 80 of about 26,093 (253)

A Detailed Study on Advanced Persistent Threats: A Sophisticated Threat

Asian Journal of Computer Science and Technology, 2018
In the present world computer networks are used to store sensitive information and to provide services for organizations and society. The growth of internet and the increased use of computers in society along with smart devices lead to the increase in cyber crimes and persistent attacks.
A. Sarkunavathi, V. Srinivasan
openaire   +2 more sources

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

A Digital Twin-Assisted Threat Modeling Framework for Predicting APT Attack Flows in Industrial Control Systems

Journal of Cybersecurity and Privacy
Industrial Control Systems (ICSs), which are essential components of critical infrastructures, are inherently complex and vulnerable to cyberattacks. Advanced Persistent Threats (APTs) that target these systems are multi-stage, coordinated attacks that ...
Gizem Erceylan, Doney Abraham, Aida Akbarzadeh, Vasileios Gkioulos, Sandeep Pirbhulal   +4 more
doaj   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

MLDSJ: a multi-level feature joint attribution method for APT group based on threat intelligence

EURASIP Journal on Information Security
Advanced persistent threat (APT) attribution is a key defense strategy that can effectively safeguard the security of critical assets and systems. Cyber threat intelligence (CTI) contains rich information about APT groups that can be leveraged for ...
Longxuan Duan, Mi Wen, Yun Xiong
doaj   +1 more source

Modeling Advanced Persistent Threats Through Organizational Roles for Adversary Emulation and Cyber Threat Intelligence

IEEE Access
Existing research and public reports on state-sponsored or state-directed Advanced Persistent Threats (APTs) describe adversary behavior mainly through tools, tactics, techniques, and procedures, but are less explicit about how long-running operations ...
Dalibor Gernhardt, Stjepan Gros, Davor Cutic   +2 more
doaj   +1 more source

Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction

Advanced Science, EarlyView.
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen, Bapan Biswas, Apinya Ngoipala, Julia Wiktor, Ujjwal Pal, Shalini Singh   +5 more
wiley   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Asymmetric Single‐Atom Catalysts Govern Diffusible and Non‐Diffusible Non‐Radical Pathways for Selective Degradation of Antibiotic Resistance Genes

Advanced Science, EarlyView.
Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao, Jun Sun, Liang Zhang, Litao Lin, Zongfeng Wan, Bingcai Pan, Sheng Tang   +6 more
wiley   +1 more source

Combating Advanced Persistent Threats: Challenges and Solutions

IEEE Network
The rise of advanced persistent threats (APTs) has marked a significant cybersecurity challenge, characterized by sophisticated orchestration, stealthy execution, extended persistence, and targeting valuable assets across diverse sectors. Provenance graph-based kernel-level auditing has emerged as a promising approach to enhance visibility and ...
Yuntao Wang 0004, Han Liu, Zhendong Li, Zhou Su, Jiliang Li   +4 more
openaire   +2 more sources