Results 221 to 230 of about 7,894,608 (291)

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Clinical Nurse Specialists' Perceptions of Competency and Self-Efficacy in Evidence-Based Practice and Implementation Science. [PDF]

Worldviews Evid Based Nurs
Shay A, McNett M, Tucker S, Fulton JS.
europepmc   +1 more source

Perceived Value of Certification for Nurses and Nurse Managers: Updated 2026 White Paper. [PDF]

Orthop Nurs
White T, Ketchum A, Cullipher A, Alger J, Arkin L, Cooper M, Jo Holloran M, Bannis A, Judkins E, Meachin D.   +9 more
europepmc   +1 more source

State of the art on advanced practice nursing role management international theories, models and frameworks: A scoping review. [PDF]

Int J Nurs Stud Adv
Han S, Duan X, Dong W, Lv J, Cao G, Zhu R, Zhang Q.   +6 more
europepmc   +1 more source

Clinical Nurse Specialists' Journey From Novice to Expert-A Systematic Mixed-Method Review. [PDF]

Scand J Caring Sci
Imeläinen SM, Kvist TA, Wright MMM, Jokiniemi KS.   +3 more
europepmc   +1 more source

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Doctor of Nursing Practice: The Role of the Advanced Practice Nurse

Seminars in Oncology Nursing, 2015
To explore the evolution and emerging roles of the Doctor of Nursing Practice (DNP) Advanced Practice Nurse (APN).Published peer reviewed literature, cancer-related professional resources, and Web-based resources.The DNP education has prepared the APN for process improvement initiatives, providing quality care, and evidence-based practice translation ...
Deborah Kirk, Walker, Shea, Polancich
openaire   +2 more sources