Results 61 to 70 of about 6,654,090 (402)
Кардиоваскулярная терапия и профилактика, 2019 Aim. To analyze main risk factors (RF) according to the epidemiological and clinical study and to determine the predictors of the development of coronary artery disease (CAD) in women.Material and methods.
F. N. Kasumova +3 more
doaj +1 more source
Multi-learner based recursive supervised training [PDF]
, 2006 In this paper, we propose the Multi-Learner Based Recursive Supervised Training (MLRT) algorithm which uses the existing framework of recursive task decomposition, by training the entire dataset, picking out the best learnt patterns, and then repeating ...
Guan, S.U. +12 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
International Journal for Equity in Health, 2019 Background Women’s empowerment may require women to change their beliefs and views about their rights and capabilities. Empowerment programs often target women who have survived sexual and gender-based violence (SGBV), with the justification that these ...
John Quattrochi +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Taurin in combined treatment of metabolic syndrome and diabetes mellitus
Терапевтический архив, 2011 In addition to information on the prevalence, etiology and pathogenesis of metabolic syndrome and type 2 diabetes mellitus, the role of insulin resistance, lipotoxicity, hyperglycemia and glucose toxicity in development complications of metabolic ...
Aleksandr Sergeevich Ametov +9 more
doaj
Вопросы современной педиатрии, 2013 Aim: to evaluate serum concentrations of cytokines (pro-inflammatory — interleukin 8 (IL8) and tumor necrosis factor α (TNF α); anti-inflammatory — IL 10; immunoregulatory — IL 6), α2-macroglobulin (MG), its immune complexes (MG-IgG) and several other ...
I. I. Klimova +2 more
doaj +1 more source
Analysis of Soft Skills-Based Approach Effectiveness in Advanced Training Program for Mining Company
Горные науки и технологии, 2020 The paper considers a specific case related to the development of a program for upgrading soft skills of employees of maintenance service in mining and processing industry, and its testing in actual practice of the production cycle rearrangement.
I. Yu. Klimov
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source