Results 71 to 80 of about 6,654,090 (402)

Clinicofunctional assessment of electric cardiac unstability in diastolic dysfunction of the left ventricle in patients with coronary heart disease

open access: yesТерапевтический архив, 2011
Aim. To study parameters characterizing electric myocardial unstability in coronary heart disease (CHD) patients with different variants of diastolic dysfunction (DD) of the left ventricle (LV). Material and methods. The study included 86 outpatients (26
Ivan Porfir'evich Tatarchenko   +9 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Comorbid anxiety disorders and quality of life in patients with an artificial cardiac pacemaker

open access: yesТерапевтический архив, 2011
Aim. To investigate correlations between anxiety disorders, quality of life (QoL)and patient's age, mode, duration and course of cardiac pacing(CP). Material and methods.
Bakhram Guseynovich Iskenderov   +7 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Training of Drivers in the Function of Road Traffic Safety

open access: yesPromet (Zagreb), 2007
The problem of the participation of young drivers in trafficaccidents is constantly present and represents a significant socialproblem. In complex and dynamic conditions of moderntraffic flows, the young drivers are exposed to various and ...
Sinan Alispahić   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

INNOVATIVE TEACHING IN THE SYSTEM OF CONTINUING TEACHERS’ EDUCATION

open access: yesВестник Кемеровского государственного университета, 2014
In the context of rapid changes and the constant updating of technology and production there is a need for graduates of a new quality, possessing not only knowledge, but also general skills, reflected in the ability to cope with life and professional ...
A. V. Kulakov, V. N. Manyukova
doaj  

Media infrastructure and tools for advanced IT training

open access: yes, 2005
S.87 ...
Caumanns, J.   +2 more
core   +1 more source

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