Results 81 to 90 of about 119,382,614 (307)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Health care systems in transition: Latvia

open access: yes, 2001
95 p.The Health Systems in Transition (HiT) series provide detailed descriptions of health systems in the countries of the WHO European Region as well as some additional OECD countries.
European Observatory on Health Systems and Policies   +1 more
core  

Advantages of the rapid HIV-1 test in occupational accidents with potentially contaminated material among health workers

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2001
In occupational accidents involving health professionals handling potentially contaminated material, the decision to start or to continue prophylactic medication against infection by Human Immunodeficiency Virus (HIV) has been based on the ELISA test ...
Alcyone Artioli MACHADO   +3 more
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Health care systems in transition: Turkmenistan

open access: yes, 2000
77 p.The Health Systems in Transition (HiT) series provide detailed descriptions of health systems in the countries of the WHO European Region as well as some additional OECD countries.
European Observatory on Health Systems and Policies   +1 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Health care systems in transition: Spain

open access: yes, 2000
135 p.The Health Systems in Transition (HiT) series provide detailed descriptions of health systems in the countries of the WHO European Region as well as some additional OECD countries.
European Observatory on Health Systems and Policies   +1 more
core  

Binary Choice Health State Valuation and Mode of Administration: Head-to-Head Comparison of Online and CAPI [PDF]

open access: yes, 2013
This article is made available open access through funding by the Medical Research Council. It is shared under a Creative Commons licence (http://creativecommons.org/licenses/by/3.0/).
Tsuchiya, Aki   +13 more
core   +1 more source

Montenegro as a high-quality health tourism destination: Trends and Perspectives [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2019
The main objective of the paper is to provide a theoretical and practical framework in order to identify the key advantages and disadvantages of Montenegro as a health tourism destination.
Anđela Jakšić- Stojanović   +2 more
doaj  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

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