Results 101 to 110 of about 585,342 (345)

Detecting adverse drug reactions for the drug Simvastatin [PDF]

open access: yesarXiv, 2014
Adverse drug reactions (ADR) are widely concerning for public health issue. In this study we propose an original approach to detect ADRs using a feature matrix and feature selection. The experiments are carried out on the drug Simvastatin. Major side effects for the drug are detected and better performance is achieved compared to other computerized ...
arxiv  

Genomics of Adverse Drug Reactions

open access: yesTrends in Pharmacological Sciences, 2017
Adverse drug reactions (ADRs) are common, are associated with morbidity and mortality, and are costly to healthcare systems. Genomic factors predispose to ADRs, but these vary depending on the drug, patient, and disease. Genomic testing can not only help to predict and prevent ADRs but can also be used in other ways (diagnosis, closer monitoring of ...
Munir Pirmohamed, Ana Alfirevic
openaire   +3 more sources

Metabolic Consequences of Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry   +2 more
wiley   +1 more source

Extracting adverse drug reactions and their context using sequence labelling ensembles in TAC2017

open access: yes, 2018
Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration.
Belousov, Maksim   +3 more
core  

Feature selection in detection of adverse drug reactions from the Health Improvement Network (THIN) database [PDF]

open access: yesarXiv, 2014
Adverse drug reaction (ADR) is widely concerned for public health issue. ADRs are one of most common causes to withdraw some drugs from market. Prescription event monitoring (PEM) is an important approach to detect the adverse drug reactions. The main problem to deal with this method is how to automatically extract the medical events or side effects ...
arxiv  

Adverse drug reactions in the elderly

open access: yesJournal of Pharmacology and Pharmacotherapeutics, 2013
Medications probably are the single most important health care technology in preventing illness, disability, and death in the geriatric population. Age-related changes in drug disposition and pharmacodynamic responses have significant clinical implications; increased use of a number of medications raises the risk that medicine-related problems may ...
Marlina Ch. Sangma   +3 more
openaire   +4 more sources

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp   +8 more
wiley   +1 more source

Adverse drug reactions reporting at a referral hospital in Zimbabwe [PDF]

open access: yes, 2004
To establish factors influencing voluntary reporting of adverse drug reactions among health workers. A second objective was to establish the level of awareness on adverse drug reaction reporting and attitudes towards the voluntary adverse drug reaction ...
Chikuni, O.   +4 more
core  

Detect adverse drug reactions for the drug Pravastatin [PDF]

open access: yesarXiv, 2013
Adverse drug reaction (ADR) is widely concerned for public health issue. ADRs are one of most common causes to withdraw some drugs from market. Prescription event monitoring (PEM) is an important approach to detect the adverse drug reactions. The main problem to deal with this method is how to automatically extract the medical events or side effects ...
arxiv  

Adverse drug reactions [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2015
Rieder, Michael, Ferro, Albert
openaire   +3 more sources

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