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Adverse drug reactions

British Medical Bulletin, 1990
The elderly have benefitted considerably from the vast increase in the range of drugs available for prescription. However it is now well recognized that the incidence in adverse drug reactions increases with age. This is mainly due to altered pharmacodynamics and pharmacokinetics as well as multiple prescribing and the effect of illness rather than the
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Adverse Reactions to Drugs

Postgraduate Medicine, 1965
The present trend toward polypharmacy increases the likelihood of adverse drug reactions and obscures the relationship of drugs to complications. Both host factors and drug factors predispose to the development of an adverse reaction. Reactions may be related to therapeutic or nontherapeutic effects of drugs. Other categories include allergic reactions
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Immunology of Adverse Drug Reactions

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1982
Adverse reactions to drugs often include an immunologic response. An understanding of immunologic mechanisms is useful in understanding the clinical manifestations of drug allergy. Predisposing factors to the development of allergic reactions to drugs include host factors as well as drug factors.
K W, Witte, D P, West
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The cost of adverse drug reactions

Expert Opinion on Pharmacotherapy, 2003
In addition to their impact on human health, adverse drug reactions (ADRs) also have significant impact on healthcare costs. These costs are essentially hospital costs, in particular arising from an increase in length of stay caused by an ADR.
Sophie, Gautier   +3 more
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Adverse Drug Reactions in Neonates

The Journal of Clinical Pharmacology, 1994
Adverse drug reactions (ADR) are uncommon causes of admission of neonates to the neonatal intensive care unit. The neonate, however, is potentially at significant risk for adverse drug reactions because of underdeveloped mechanisms and systems for handling drugs (the Gray Baby Syndrome with chloramphenicol as a classic example), the fact that infants ...
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Pharmacogenetics of Adverse Drug Reactions

2018
Adverse drug reactions (ADRs) are an important cause of morbidity and mortality. Genetic factors predispose to many ADRs, affecting susceptibility to both type A and type B reactions. The overall contribution of genetics will vary according to drug and ADR, and should be considered when attempting to predict and prevent ADRs.
Osanlou O, Pirmohamed M, Daly AK
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Ocular adverse drug reactions

Expert Opinion on Drug Safety, 2003
Drug-induced ocular side effects are described according to recent reports from the literature, the National Registry of Drug-Induced Ocular Side Effects, the World Health Organization (WHO) and the FDA. Adverse events are categorised as certain, probable/likely, possible, unlikely, conditional/unclassified and unassessable/unclassifiable where ...
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Adverse drug reactions

The Lancet, 2001
G M, Shenfield, J, Jacka
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Adverse drug reactions

Indian Journal of Cancer, 2009
Gajula, V, Bogu, S, Vutukuru, A
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Adverse reactions to drugs

In Practice, 1983
P, Keen, A, Livingston
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