Safety profile of oxcarbazepine: results from a prescription-event monitoring study [PDF]
Purpose: To monitor safety of oxcarbazepine, prescribed in primary care in England, using prescription-event monitoring (PEM). Methods: Postmarketing surveillance using observational cohort technique of PEM.
Buggy, Y.+3 more
core +1 more source
Yellow Fever Virus Vaccine–associated Deaths in Young Women
Yellow fever vaccine–associated viscerotropic disease is a rare sequela of live-attenuated virus vaccine. Elderly persons and persons who have had thymectomies have increased susceptibility.
Stephen J. Seligman
doaj +1 more source
Complementing the US Food and Drug Administration Adverse Event Reporting System With Adverse Drug Reaction Reporting From Social Media: Comparative Analysis [PDF]
Zeyun Zhou, Kyle E. Hultgren
openalex +1 more source
Low‐Activation Compositionally Complex Alloys for Advanced Nuclear Applications—A Review
Low‐activation compositionally complex alloys (LACCAs) are advanced metallic materials primarily composed of low‐activation elements, offering advantages such as rapid compliance with operational standards and safe recyclability. This review highlights their potential for extreme high‐temperature irradiation environments as structural materials for ...
Yangfan Wang+8 more
wiley +1 more source
Data Mining and Analytical Models to Predict and Identify Adverse Drug-drug Interactions [PDF]
The use of multiple drugs accounts for almost 30% of all hospital admission and is the 5th leading cause of death in America. Since over 30% of all adverse drug events (ADEs) are thought to be caused by drug-drug interactions (DDI), better identification and prediction of administration of known DDIs in primary and secondary care could reduce the ...
arxiv
AbstractPurposeA continuous systematic review of all combinations of drugs and suspected adverse reactions (ADRs) reported to a spontaneous reporting system, is necessary to optimize signal detection. To focus attention of human reviewers, quantitative procedures can be used to sift data in different ways.
Eugène van Puijenbroek+6 more
openaire +5 more sources
Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records. [PDF]
Drug-drug interactions (DDI) account for 30% of all adverse drug reactions, which are the fourth leading cause of death in the US. Current methods for post marketing surveillance primarily use spontaneous reporting systems for learning DDI signals and ...
Bauer-Mehren, Anna+4 more
core +5 more sources
Linked health data for pharmacovigilance in children : Perceived legal and ethical issues for stakeholders and data guardians [PDF]
Peer reviewedPublisher ...
Bond, Christine M+4 more
core +2 more sources
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng+12 more
wiley +1 more source
Co-training for Extraction of Adverse Drug Reaction Mentions from Tweets [PDF]
Adverse drug reactions (ADRs) are one of the leading causes of mortality in health care. Current ADR surveillance systems are often associated with a substantial time lag before such events are officially published. On the other hand, online social media such as Twitter contain information about ADR events in real-time, much before any official ...
arxiv